新疆维吾尔族30～80 岁人群代谢综合征调查及三种诊断标准的对比研究

蒋升; 张莉; 邵亮; 严丽君; 伊力多斯·阿里什; 谢自敬

Abstract

蒋升,张莉,邵亮,严丽君,伊力多斯·阿里什,谢自敬.新疆维吾尔族30～80 岁人群代谢综合征调查及三种诊断标准的对比研究[J].Chinese journal of Epidemiology,2011,32(8):756-759

新疆维吾尔族30～80 岁人群代谢综合征调查及三种诊断标准的对比研究

Epidemiological investigation and comparison of three different diagnostic criteria regarding metabolic syndrome among population age 30-80 in Xinjiang Uigur areas

Received:March 08, 2011

DOI：

KeyWord: 代谢综合征诊断标准维吾尔族

English Key Word: Metabolic syndrome Diagnostic criteria Uigur population

FundProject:国家自然科学基金（30560055）

Author Name	Affiliation	E-mail
Jiang Sheng	Department of Endocrinology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China
Zhang Li	Xinjiang Uigur Autonomous Region General Army Hospital of Armed Police
Shao Liang	Xinjiang Uigur Autonomous Region General Army Hospital of Armed Police
Yan Li-jun	Xinjiang Uigur Autonomous Region General Army Hospital of Armed Police
Yldos Alishi	Department of Endocrinology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China
Xie Zi-jing	Department of Endocrinology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China	xjjsh01@sina.com

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Abstract:

目的<\b>了解新疆维吾尔族人群代谢综合征（MS）患病情况,比较美国国家胆固醇教育计划成人治疗组第三次报告（ATPⅢ）、国际糖尿病联盟（IDF）和中华医学会糖尿病学分会（CDS）建议的MS诊断标准在维吾尔族人群中应用的差异。方法<\b>对新疆地区2053 名维吾尔族30～80 岁居民进行横断面调查,根据3 种诊断标准分别计算MS患病率,分析不同诊断标准下MS异常组分及危险因素聚集的检出情况,比较3 种诊断标准在维吾尔族人群中的一致性。结果<\b>（1）3 种诊断标准患病率（标化患病率）分别为35.80%（29.64%）、39.41%（35.88%）和23.72%（19.17%）；（2）3 种标准对MS 患者3 个以上危险因素聚集的检出率分别为98.64%、97.90%和92.81%；（3）3 种诊断标准在维吾尔族人群中应用的一致性两两比较,ATPⅢ标准与IDF 标准的一致性较好（一致率为0.9026,Youden 指数为0.7928,Kappa 值为0.7801）,CDS标准与另外两种标准（ATPⅢ和IDF）的一致性不高。结论<\b>在新疆维吾尔族人群中应用3 种MS诊断标准,获得的患病率、危险组分聚集情况和一致性差异较大,IDF 标准检出率最高,ATPⅢ标准对危险因素聚集检出率最高,且两者一致性较好,优于CDS标准。

English Abstract:

Objective To investigate the prevalence of metabolic syndrome（MS）among Xinjiang Uigur population aged 30-80 and to compare the differences of the three diagnostic criteria used for MS. The three diagnostic criteria were developed by the National Cholesterol Education Program（ATPⅢ），International Diabetes Federation（IDF）and Chinese Medical Association Diabetes Branch（CDS）.Methods A cross-sectional study was conducted on 2053 Xinjiang Uigur people aged 30-80. The prevalence of MS and the degree of agreement were both calculated according to the three definitions. The results of MS components were also analyzed.Results （1）According to the three definitions（ATPⅢ，IDF and CDS），the prevalence and adjusted prevalence rates of MS were 35.80%（29.64%），39.41%（35.88%）and 23.72%（19.17%）.（2）According to the three definitions （the ATP Ⅲ ，IDF and CDS），the prevalence rates of subjects who had at least 3 risk factors were 98.64%，97.90% and 92.81%.（3）Among all the subjects with MS，the MS diagnostic criteria of ATP Ⅲ and IDF were in good accordance with the Kappa index（0.7801），Youden index（0.7928）and the concordance rate （0.9026）. CDS was in relatively weak agreement when comparing with other definitions （ATP Ⅲ and IDF）.Conclusion Our findings revealed big differences regarding the prevalence rates，the degree of agreement and the aggregation of risk components on MS among Xinjiang Uigur population. The detection rate of IDF criteria on MS and the highest while detection rate of ATPⅢ criteria on subjects presented at least 3 risk factors were the highest. The concordance of ATPⅢ criteria and IDF seemed to be a better one.

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