| 卢昕,阚飙,刘剑锋,张勤.全基因组关联研究理论及其在流行病中的应用[J].Chinese journal of Epidemiology,2011,32(10):1043-1045 |
| 全基因组关联研究理论及其在流行病中的应用 |
| Theory of genome-wide association study and its application in epidemic diseases |
| Received:March 02, 2011 |
| DOI：10.3760/cma.j.issn.0254-6450.2011.10.020 |
| KeyWord: 全基因组关联研究 流行病 |
| English Key Word: Genome-wide association study Epidemic diseases |
| FundProject:国家重点基础研究发展计划（973计划）(2006CB 102104); 国家自然科学基金(30972092); 国家高技术研究 发展计划（863计划）(2008AA101002); 国家重大科技专项 (2008ZX 10004-009,2009ZX 10601) |
| Author Name | Affiliation | E-mail | | LU Xin | State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Key Laboratory Animal Genetics and Breeding of the Ministry of Agricultural, State Key Laboratory of AgroBiotechnology, College of Animal Science and Technology, China Agricultural University | | | KAN Biao | State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | LIU Jian-fen | Key Laboratory Animal Genetics and Breeding of the Ministry of Agricultural, State Key Laboratory of AgroBiotechnology, College of Animal Science and Technology, China Agricultural University | | | ZHANG Qin | Key Laboratory Animal Genetics and Breeding of the Ministry of Agricultural, State Key Laboratory of AgroBiotechnology, College of Animal Science and Technology, China Agricultural University | qzhang@cau.edu.cn |
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| Abstract: |
| 全基因组关联研究(GWAS)利用遍布于全基因组范围的分子标记（主要为单核苷酸多态性，SNP）并借助强大统计学工具，对影响某些复杂性状如疾病易感的遗传变异进行鉴定和分析。 |
| English Abstract: |
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