中国6市7～1 6岁中小学生血脂水平现状调查

朱建芳; 梁黎; 傅君芬; 巩纯秀; 熊丰; 刘戈力; 罗飞宏; 陈少科

Abstract

朱建芳,梁黎,傅君芬,巩纯秀,熊丰,刘戈力,罗飞宏,陈少科.中国6市7～1 6岁中小学生血脂水平现状调查[J].Chinese journal of Epidemiology,2012,33(10):1005-1009

中国6市7～1 6岁中小学生血脂水平现状调查

Survey on the levels of lipids in school-aged children of Beijing，Tianjin，Hangzhou，Shanghai，Chongqing and Nanning cities

Received:April 11, 2012

DOI：

KeyWord: 血脂非高密度脂蛋白胆固醇学龄期儿童肥胖

English Key Word: Lipids Non-high-density lipoprotein cholesterol Children of school-age Obesity

FundProject:“十一五“国家科技支撑计划(2009BAl80801)

Author Name	Affiliation	E-mail
Zhu Jianfang	Department, Endocrinology, Children’S HospitalAffiliated Medical College of Zhefiang University, Hangzhou 310003, China
Liang Li	Department, Endocrinology, Children’S HospitalAffiliated Medical College of Zhefiang University, Hangzhou 310003, China	zdliangli@163.com
Fu Junfen	Department, Endocrinology, Children’S HospitalAffiliated Medical College of Zhefiang University, Hangzhou 310003, China
Gong Chunxiu	Department of Endocrinology. Bering Children’S Hospital
Xiong Feng	Department of Endocrinology, Children’s Hospital of Chongqing Medical University
Liu Geli	Department ofPediatrics, Tianfin Medical University General Hospital
Luo Feihong	Department of Endocrinology. Children’s Hospital of Fudan University
Chen Shaoke	Department of Pediatrics, Maternal and Child Health Care of Guangxi Zhuang Autonomous Region

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Abstract:

目的解中国汉族学生血脂水平现状，为制定儿童青少年血脂异常防治策略提供依据。方法选择有地域代表的北京、天津、杭州、上海、重庆和南宁6市2010年在校7～16岁中小学生共20 191名(男性10 669名，女性9522名)为调查对象；按血脂测定标准化方法测定空腹甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆同醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平，计算非高密度脂蛋白胆固醇(non-HDL-C)。结果果(1)7～16岁儿童青少年每岁年龄组的TG(95百分位数，P。，)为1.26～1.88 mmol／L，TC(P。，)为4.80～5.46 mmol／L，LDL-C(P。s)为2.67～3.27mmol／L.non-HDL-C(P。，)为3.36～3.9l mmol／L，与年龄无明甚相关性(P>0.05)HDL-C(P，)波动于1.08～0.83 mmol／L，HDL-C与年龄的相关性分析提示差异有统计学意义(P结论在儿童青少年期，年龄不是影响TG、TC、LDL-C水平的主要因素，但HDL-C水平随年龄增长有一定下降趋势；非肥胖组血脂水平明显优于肥胖组，且东郭地区优于北部及中西部。

English Abstract:

ObjectiveTo investigate the lipid levels of Hart ethnicity Chinese children atschool-age，to provide objective data for the formnlation of prevention and management strategy regarding dyslipidemia children and adolescents.Methods20 1 9 1 children(with 1 0 669 boys and 9522 girls)aged 7 to 1 6 years old from 6 representative geographical areas，including Beijing，Tianjin，Hangzhou，Shanghai，Chongqing and Nanning，were surveyed in a randomly selectedclustered sample in China.Data on fasting blood triglyceride(TG).total cholester01(TC)，low-density lipoprotein cholester01(LDL-C)and high-density lipoprotein cholesterol(HDL-C)1evelswere measured Non-high.density lipoprotein cholester01(non-HDL-C)levels were calculated with data collection，entry.and collation were under the same criteria.Results(1)In the 7-l 6 year-old group.TG(P9)fluctuated between).26 mmol／L and 1.88 mmol／L，while TC(Pqj)was between 4.80mmol／L and 5.46mmol／L.LDL-C(P95)was between 2，67mmol／L and 3.27mmol／Lwhilenon-HDL-C(P。。)was between 3.36 mmol／L and 3.9lmmol／L，sugesting that age did not seem to be an affectingfactor for the lipid 1evel(P>0.05).The level of HDL-C(P5)fluctuated bctween 1.08 mmol／L and 0.83 mmol／L.and the dependability analysis on HDL-C and age showed statistically significantdif’fefence(P<0.01.r=-0.274).(2)In the 7-9 year-old group，the levels ofTG，TC，LDL-C and non-HDL-C of boys were lower but the HDL-C level was higher than in girls.However.i11 the 1 0-l 6year-old group.the 1evels of five lipids of boys were a1110wer than in girls，with a11 the differences statistically significant(P<0.05).(3)The levels of TG，TC，LDL-C and non-HDL-C in the obesegroup were significantly higher than those in non-obesity group.as HDL-C was significantly lower than in non-obese group(P<0.0 1).Incidence rates of single and multiple dyslipidemia in obese groupwere significantly higher than in non-obese group(P<0.01).(4)Grouped by region，the abnormal rates of TG were descending，with the ranking as North(10.4％)，Midwest(9.7％)and East(8 3％).while the abnormal rates of TC were descending with the ranking as Midwest(6.0％).Nonh(5.2％) and East(4.8％)，The abnormal rates ofLDL-Cwere descending as the ranking of North(3.1％)，East (2.6％)and Midwest(0.9％).with the abnormal rates of non-HDL-C were descending as Midwest(6.5％).North(4 2％)and East(3.6％).The abnormal rates of HDL-C were descending as Midwess (14.2％)。North(5.7％)and East(5.5％).A1l the differences in the above-said iterns were statisticallysignificant(P<0。05).(5)According to the standards ofhyperlipidemia formulated by the American Academy of Pediatrics，the incidence rates of abnormal TG，TC.LDL-C.non.HDL-C.HDL-C were 9.4％，5.4％，2.2％，4.8％，8.6％respectively.Conclusion(1)Levels of lipids were affected by many factors.but age was not one of them in children and adolescents.However.HDL-C was decliningalong with the inerease of age.to some extent(2)Giris had a relatively protective tendency through the increasing HDL-C level when they entered the puberty years.(3)Lipids levels in non-obese groupwere significantly better than the obese group.(4)The lipids 1evels of children and adolescents in the Eastern region of the country were better than that in the northern and mid-western areas.

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