Abstract
郑卫军,沈祥峰,周驰.糖调节受损者睡眠质量与糖尿病发病关系的研究[J].Chinese journal of Epidemiology,2012,33(11):1141-1143
糖调节受损者睡眠质量与糖尿病发病关系的研究
Association between the quality of sleep and the occurrence of diabetes among people with impaired glucose regulation
Received:April 17, 2012  
DOI:10.3760/cma.j.issn.0254-6450.2012.11.010
KeyWord: 糖调节受损  糖尿病  睡眠质量  队列研究
English Key Word: Impaired glucose regulation  Diabetes  Sleep quality  Cohort study
FundProject:浙江省教育厅研究项目(Y201018233);浙江中医药大学人才项目
Author NameAffiliationE-mail
ZHENG Wei-jun Zhejiang Chinese Medical University College of Basic Medical Science, Hangzhou 310053, China deardangjun@163.Com 
SHEN Xiang-feng Zhejiang Chinese Medical University College of Basic Medical Science, Hangzhou 310053, China  
ZHOU Chi Zhejiang University School of Public Health1.  
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Abstract:
      目的 探讨糖调节受损者睡眠质量与糖尿病发病的关系.方法 采集1136名队列人群睡眠时长和失眠严重程度的相关信息,跟踪和总结其2年后糖调节受损者转归情况,并应用泊松回归模型探讨睡眠质量与糖调节受损转归的关系.结果 调整混杂因素后,与7~9h的睡眠时长相比,睡眠时长<7h的群体RR=1.77 (P<0.001),睡眠时长≥9h的群体RR=1.45(P=0.067).与失眠严重程度≤14分相比,>14分的群体RR=1.58 (P<0.001).结论 糖调节受损群体糖尿病发病风险与睡眠缺乏存在一定关系,睡眠质量较差的糖调节受损群体将更容易在2年之内转归为糖尿病.
English Abstract:
      Objective To understand the association between people under impaired glucose regulation (IGR) with poor quality of sleep and the occurrence of diabetes. Methods Based on a cohort of 1136 persons with IGR, the present study would include information on the duration of sleep and severity of insomnia. The cohort was followed for two years and the outcomes of impaired glucose regulation were summarized. Poisson regression was employed to analyze the relationship between the quality of sleep and the occurrence of diabetes. Results After the confounders were adjusted, when compared with 7-9 h sleep duration, the less than 7 h sleep duration showed a RR value of 1.77 (P<0.001) while more than 9 h sleep duration had a RR value of 1.45 (P=0.067). When compared data from people having less than 14 scores of the Insomnia Severity Index (ISI), those people with more than 14 scores had a RR value of 1.58 (P<0.001). Conclusion Causal relationship between the quality of sleep and the occurrence of diabetes did exist among the IGR population while the poor quality of sleep might increase the risk of diabetes at the end of the two-year following-up program.
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