熊菲,邓思燕,万朝敏.亚急性硬化性全脑炎的研究现状及进展[J].Chinese journal of Epidemiology,2012,33(11):1193-1195 |
亚急性硬化性全脑炎的研究现状及进展 |
Current state on research arecs regarding subacute sclerosing panencephalitis (document analysis) |
Received:May 15, 2012 |
DOI:10.3760/cma.j.issn.0254-6450.2012.11.022 |
KeyWord: 亚急性硬化性全脑炎 中枢神经系统感染 麻疹病毒 |
English Key Word: Subacute sclerosing panencephalitis Central nervous system infections Measles virus |
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Author Name | Affiliation | E-mail | XIONG Fei | Department of Pediatrics, West China Second University Hosphal, Sichuan University, Chengdu 610041, China | | DENG Si-yan | Department of Pediatrics, West China Second University Hosphal, Sichuan University, Chengdu 610041, China | | WAN Chao-min | Department of Pediatrics, West China Second University Hosphal, Sichuan University, Chengdu 610041, China | wcm0220@sina.Com |
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Abstract: |
亚急性硬化性全脑炎(subacute sclerosing panencephalitis,SSPE)是由有缺陷的麻疹病毒持续感染所致的中枢神经系统慢性进行性退行性致死性疾病,其预后差,病死率极高.1933年Dawson首先报道该病,1969年Greenfield从患者脑组织中分离出麻疹病毒后,将其正式定义为SSPE.国外病例报告较多,而我国研究报道较少,目前仅有5例病例报告.本文通过查阅近10年国外文献的SSPE病例报告,分析总结临床特征及预后,阐述其研究现状. |
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