Abstract
黄学勇,李幸乐,胡晓宁,杜燕华,许玉玲,卫海燕,陈豪敏,许汴利.肠道病毒71型外壳蛋白VPl基因克隆、表达及活性鉴定[J].Chinese journal of Epidemiology,2013,34(5):541-542
肠道病毒71型外壳蛋白VPl基因克隆、表达及活性鉴定
Cloning，expremion and activity determination of capsid protein VPI of enterovirus type 71
Received:December 22, 2012  
DOI：
KeyWord: 肠道病毒71型  外壳蛋白VPI  原核表达  抗原性
English Key Word: nterovirus type 71  Capsid protein VPl  Prokaryotic express  Antigenicity
FundProject:河南省科技攻关计划(122102310268);河南省医学科技重大攻关项目(201001015);河南省卫生科技创新型人才工程中青年科技创新人才项目
Author NameAffiliationE-mail
HUANG Xueyong Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
LI xingle Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
HU xiaoning Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
DU Yanhua Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
XU Yuling Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
WEI Haiyan Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
CHEN Haomin. XU Bianli Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China  
许汴利 Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prvention．Zhengzhou 450016．China xubl@hncdc．com．cn 
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Abstract:
      肠道病毒71型(EV71)和柯萨奇病毒A组16型(CoxAl6)是引起手足口病最为常见肠道病毒，其中EV71是引起当前我国手足口病的病原优势株?。目前临床对EV71感染以对症治疗为主，尚无有效的抗病毒药物，研制安全有效的疫苗和早期诊断试剂是预防控制手足口病疫情的经济有效地措施，为此进行以下相关研究。
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