细胞色素P450 2E1基因多态性与小细胞肺癌相关性分析

曹蕾; 何冰; 林佳; 王宏戈; 饶娟; 刘英文; 张雪梅

Abstract

曹蕾,何冰,林佳,王宏戈,饶娟,刘英文,张雪梅.细胞色素P450 2E1基因多态性与小细胞肺癌相关性分析[J].Chinese journal of Epidemiology,2013,34(10):1048-1049

细胞色素P450 2E1基因多态性与小细胞肺癌相关性分析

Association of cytochrome P450 2El gene polymorphism and the risk of small-cell lung cancer

Received:May 29, 2013

DOI：10．3760/cma．j．issn．0254—6450．2013．10．026

KeyWord:

English Key Word: all．cell lung cancer|Cytochrome P450 2El gene|Single nucleotide polymorphism

FundProject:国家自然科学基金(81272613)；教育部新世纪优秀人才支持计划(NCET-11—0933)；全国优秀博士学位论文作者专项基金(201274)

Author Name	Affiliation	E-mail
CAO Lei	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).	jyxuemei@gmail.tom
HE Bing	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).
LIN Gui	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).
WANG Hong-ge	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).
RAO Juan	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).
LIU Ying-wen	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).
ZHANG Xue-mei	This work was supported by grants from the National NaturalScience Foundation ofChina(No. 81272613), Programfor New Century Excellent Talents in University(No. NCET-1 1-0933)and Foundation for the Author of National Excellent Doctoral Dissertation ofChina(No. 201274).

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Abstract:

小细胞肺癌在肺癌中恶性度极高。细胞色素P450 2El基因(CYP2E1)作为一种重要的I相代谢酶参与多种致癌物的代谢，其位点多态性可影响自身表达…。本研究采用病例对照研究方法，分析CYP2E1—1239位点多态性与小细胞肺癌发病风险的关系。

English Abstract:

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