无锡市2005－2010 年儿童流感相关超额住院估计

冯录召; 费方荣; 李飒; 钱燕华; 祖荣强; 余宏杰

Abstract

冯录召,费方荣,李飒,钱燕华,祖荣强,余宏杰.无锡市2005－2010 年儿童流感相关超额住院估计[J].Chinese journal of Epidemiology,2014,35(6):699-703

无锡市2005－2010 年儿童流感相关超额住院估计

Influenza-associated-excess-hospitalization in children，Wuxi city，Jiangsu province，2005-2010

Received:April 09, 2014

DOI：

KeyWord: 季节性流感甲型H1N1 流感超额住院负二项回归儿童

English Key Word: Seasonal influenza A（H1N1）pdm Excess hospitalization Negative binomial regression Children

FundProject:中美新发和再发传染病合作项目（5U2GGH000018-02）;无锡市卫生局重大项目（G201201）

Author Name	Affiliation	E-mail
Feng Luzhao	Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Fei Fangrong	Zhejiang Provincial Center for Disease Control and Prevention
Li Sa	Wuxi City Center for Disease Control and Prevention
Qian Yanhua	Jiangsu Provincial Center for Disease Control and Prevention
Zu Rongqiang	Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China
Yu Hongjie	###############################################################################################################################################################################################################################################################	yuhj@chinacdc.cn

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Abstract:

目的估计2005－2010 年无锡市0～14 岁儿童流感相关超额住院率。方法收集无锡市14 家二级及以上医院流感及肺炎、呼吸系统疾病住院资料及我国南方病毒学监测数据，拟合负二项回归模型，估计流感相关超额住院情况。结果 2005－2010 年无锡市0～14 岁儿童住院率平均为91.6‰（79.2‰～99.3‰），其中，呼吸系统疾病住院占总住院人数的54.2%，流感及肺炎住院占38.1%。年均流感及肺炎超额住院率为1.28‰（95%CI：0.29‰～4.84‰），呼吸系统疾病超额住院率为2.18‰（95%CI：0.61‰～6.79‰）。甲型H1N1 流感在2009 年导致993 例流感及肺炎超额住院和1 042 例呼吸系统疾病超额住院，对应的超额住院率分别为1.14‰和1.20‰。结论无锡市季节性流感和甲型H1N1 流感大流行对0～14 岁儿童产生相当的超额住院。

English Abstract:

Objective To estimate the rates due to influenza-associated-excesshospitalization in children aged 0-14 years in Wuxi city，Jiangsu province in 2005-2010. Methods We collected data on hospitalization due to influenza，pneumonia and other respiratory diseases from fourteen 2nd level or above hospitals in Wuxi，as well as data on influenza virological surveillance in southern China to fit the negative binomial regression models，to estimate the rate on influenzaassociated- excess hospitalization. Results During 2005-2010，an average annual hospitalization rate appeared as 91.6‰（79.2‰ -99.3‰）. Among the total hospitalization eases，respiratory diseases accounted for 54.2%，while both influenza and pneumonia accounted for 38.1%. The average annual influenza- associated-excess-hospitalization rates due to influenza and pneumonia appeared as 1.28‰ （95% CI：0.29‰ -4.84‰），while 2.18‰（95% CI：0.61‰ -6.79‰）due to respiratory diseases. In 2009，A（H1N1）pdm induced influenza pandemic caused 993 excess hospitalizations due to influenza/pneumonia and 1 042 excess hospitalizations due to respiratory diseases，with rates as 1.14‰ and 1.20‰ respectively. Conclusion Both seasonal and pandemic A（H1N1）pdm influenza caused considerable burden on hospitalization in children aged 0-14 years inWuxi.

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