Abstract
冯一冰,王棵,王定明,董芬,余杨文,潘利,李凌,刘涛,曾宪嘉,孙良先,朱广瑾,冯逵,平波,许可,庞兴龙,陈婷,潘慧,马瑾,钟勇,王璐,单广良.贵州地区汉族居民糖尿病患病情况及相关危险因素研究[J].Chinese journal of Epidemiology,2015,36(11):1220-1225
贵州地区汉族居民糖尿病患病情况及相关危险因素研究
Prevalence and associated risk factors of diabetes among ethnic Han residents in Guizhou
Received:May 21, 2015  
DOI:10.3760/cma.j.issn.0254-6450.2015.11.008
KeyWord: 糖尿病  空腹血糖  患病率  危险因素
English Key Word: Diabetes mellitus  Fast plasma glucose  Prevalence  Risk factors
FundProject:
Author NameAffiliationE-mail
Feng Yibing National Center for STD/AIDS Prevention and Control Chinese Center for Disease Control and Prevention, Beijing 102206, China  
Wang Ke Peking Union Medical College and Chinese Academy of Medical Science  
Wang Dingming Guizhou Provincial Center for Disease Control and Prevention  
Dong Fen Peking Union Medical College and Chinese Academy of Medical Science  
Yu Yangwen Guizhou Provincial Center for Disease Control and Prevention  
Pan Li Peking Union Medical College and Chinese Academy of Medical Science  
Li Ling Guizhou Provincial Center for Disease Control and Prevention  
Liu Tao Guizhou Provincial Center for Disease Control and Prevention  
Zeng Xianjia Peking Union Medical College and Chinese Academy of Medical Science  
Sun Liangxian Guizhou Provincial Center for Disease Control and Prevention  
Zhu Guangjin Peking Union Medical College and Chinese Academy of Medical Science  
Feng Kui Peking Union Medical College and Chinese Academy of Medical Science  
Ping Bo Longli County Center for Disease Control and Prevention  
Xu Ke Peking Union Medical College Hospital  
Pang Xinglong Peking Union Medical College Hospital  
Chen Ting Peking Union Medical College Hospital  
Pan Hui Peking Union Medical College Hospital  
Ma Jin Peking Union Medical College Hospital  
Zhong Yong Peking Union Medical College Hospital  
Wang Lu National Center for STD/AIDS Prevention and Control Chinese Center for Disease Control and Prevention, Beijing 102206, China wanglu64@163.com 
Shan Guangliang Peking Union Medical College and Chinese Academy of Medical Science guangliang_shan@hotmail.com 
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Abstract:
      目的 了解贵州地区汉族居民空腹血糖水平,分析糖尿病相关危险因素。方法 采用多阶段整群抽样方法,选取20~80岁汉族居民进行调查。调查内容包括问卷调查、体格检查和实验室检测。比较城乡不同年龄、性别人群空腹血糖水平和糖尿病相关危险因素。结果 共纳入研究对象2 967人,城镇居民空腹血糖平均值高于农村(5.21 mmol/L vs. 5.03 mmol/L,P< 0.001),男性高于女性(5.23 mmol/L vs. 5.09 mmol/L,P=0.003),血糖水平有随年龄增长的趋势(P< 0.001)。城镇居民糖尿病标化患病率为6.01%(粗率7.45%),其中男性显著高于女性(P< 0.001),随年龄增长患病率升高。农村居民标化患病率为3.47%(粗率3.77%),性别差异无统计学意义,随年龄增长患病率升高。相同年龄性别下,≥40岁城镇居民患病率高于农村居民。糖尿病患者中知晓率为56.59%,治疗率为84.47%,控制率为41.38%。多因素分析显示,男性发病风险高于女性、年龄≥40岁发病风险升高、有糖尿病家族史、经常进行身体锻炼、高血压、高甘油三酯者糖尿病的发病风险增加。结论 贵州汉族居民糖尿病患病率较高,城乡患病率差异大,半数以上糖尿病患者治疗后血糖未达到控制水平,糖尿病知晓率、治疗率及控制率仍需进一步提高。
English Abstract:
      Objective To understand the fast plasma glucose (FPG) level and the epidemiologic characteristics of diabetes in ethnic Han residents of Guizhou province. Methods The survey was conducted among the ethnic Han residents aged 20-80 years, who were selected through multi stage cluster sampling in Guizhou. Basic laboratory test, physical examination were performed for each subject. Results A total of 2 967 subjects were surveyed. The average FPG level was 5.21 mmol/L for urban residents and 5.03 mmol/L for rural residents,(P< 0.001) and the average FPG level was higher in males than in females (5.23 mmol/L vs. 5.09 mmol/L, P=0.003). The FPG level increased with age (P< 0.001). In urban residents, the standardized prevalence of diabetes was 6.01% (crude prevalence:7.45%), higher in males than in females (P< 0.001) and increased with age. In rural residents,the standardized prevalence of diabetes was 3.47% (crude prevalence:3.77%) and increased with age, but there was no sex specific difference in diabetes prevalence. The awareness rate of self diabetes status was 56.59%, the treatment rate was 84.47% and the plasma glucose control rate was 41.38%. Multiple logistic regression analysis indicated that risk factors for diabetes included being male, older than 40 years, family history of diabetes, frequent physical exercise, hypertension, high triglycerid level. Conclusion The prevalence of diabetes was high in ethnic Han residents in Guizhou, the differences in diabetes prevalence between urban area and rural area was statistical significant. More than half of the patients' FPG level had not been under control after treatment. The awareness rate of self diabetes status, the treatment rate and the control rate of diabetes should be improved.
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