| 汤后林,韩晶,李健,许娟,毛宇嵘.2010年全国新报告HIV/AIDS病例接受规范化随访及效果分析[J].Chinese journal of Epidemiology,2016,37(12):1602-1607 |
| 2010年全国新报告HIV/AIDS病例接受规范化随访及效果分析 |
| Effects of standardized follow-up program among newly diagnosed HIV/AIDS cases in 2010 |
| Received:July 12, 2016 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.12.010 |
| KeyWord: 艾滋病 随访 性行为 抗病毒治疗 效果 |
| English Key Word: HIV/AIDS Follow-up Sexual behavior Antiretroviral Therapy Effect |
| FundProject: |
| Author Name | Affiliation | E-mail | | Tang Houlin | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Han Jing | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Li Jian | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Xu Juan | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Mao Yurong | National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | mayor@chinaaids.cn |
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| Abstract: |
| 目的 分析2010年全国新报告HIV/AIDS病例（HIV/AIDS）接受规范化随访的效果。方法 使用艾滋病综合防治数据信息系统截至2015年12月31日的病例报告历史卡片和随访定时数据库，筛选出2010年新报告的病例，对其在2010-2015年期间接受规范化随访的情况进行分析，通过安全性行为比例、成功转介抗病毒治疗比例以及死亡情况等指标的变化评估随访效果。结果 2010年新报告、年龄≥14周岁的HIV/AIDS共40 335例，其中，男性占70.4%，汉族占72.0%，25～44岁年龄组占56.7%，小学及以下文化程度者占62.3%，未婚者占53.9%；异性传播、注射吸毒和同性传播分别占65.8%、15.0%和11.7%。40 335例HIV/AIDS每年接受规范化随访的比例逐年上升，趋势 χ2检验结果差异有统计学意义（χ2=3 749.77，P<0.01）；接受随访干预后，发生危险性行为的比例明显下降，2011-2015年安全性行为比例均>90%（趋势 χ2=16 971.98，P<0.01），但从同一病例角度，其接受全程规范化随访期间安全性行为比例为86.1%；符合抗病毒治疗标准的病例当年成功转介治疗的比例从2010年的56.5%上升到2015年的83.2%，呈现明显的上升趋势（趋势 χ2=2 504.86，P<0.01），注射毒品感染的HIV/AIDS接受抗病毒治疗的比例较低（2015年为64.7%）；HIV/AIDS病死率从2010年新报告时的12.4%下降到2015年的2.4%（趋势 χ2=4 935.89，P<0.01）。结论 实施规范化随访后，HIV/AIDS采取安全性行为的比例和及时转介接受抗病毒治疗的比例逐年上升，病死率有所降低。 |
| English Abstract: |
| Objective To analyze the effects of a follow-up program among newly diagnosed HIV/AIDS cases in 2010 in China. Methods Database was downloaded on January, 2016 from both HIV/AIDS Case Reporting and Follow-up Cards. Information related to newly diagnosed HIV/AIDS cases in 2010 was extracted from the database. Information on follow-up intervention programs, CD4 testing, antiretroviral treatment, sexual behavior and mortality from 2010 to 2015 were analyzed. Results Of the newly diagnosed HIV/AIDS cases in 2010, 70.4% were men and 72.0% with Han ethnicity. Heterosexual transmission accounted for 65.8%. The proportion of having received standardized follow-up increased significantly, with an annually upward trend (trend χ2=3 749.77, P<0.01). The proportions of sexual risk behaviors decreased significantly, with safe sexual behaviors over 90%, and having yearly upward trend (trend χ2=16 971.98, P<0.01). Among those eligible for antiretroviral therapy, the proportion of initiation the therapy increased from 56.5% in 2010 to 83.2% in 2015, with significant upward trend, annually (trend χ2=2 504.86, P<0.01). Over the same period, the proportion of deaths decreased from 12.4% in 2010 to 2.4% in 2015, with significant annual downward trend (trend χ2=4 935.89, P<0.01). Conclusion The standardized follow-up intervention program included the contents of:CD4 testing; counseling and timely referrals to receive antiretroviral therapy etc., which were correlated to the reduction on both high risk sexual behaviors and deaths. |
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