Abstract
李佳媚,刘丹朦,张小凤,屈鹏飞,颜虹.陕西省农村育龄妇女围孕期产检次数与新生儿低出生体重间关系的研究[J].Chinese journal of Epidemiology,2017,38(4):478-481
陕西省农村育龄妇女围孕期产检次数与新生儿低出生体重间关系的研究
Study on the relationship between frequencies of prenatal care and neonatal low birth weight in women of childbearing age from rural areas of Shaanxi province
Received:September 01, 2016  
DOI:10.3760/cma.j.issn.0254-6450.2017.04.013
KeyWord: 低出生体重  围孕期  产检次数  广义Poisson回归模型
English Key Word: Low birth weight  Perinatal period  Prenatal care times  Generalized Poisson regression
FundProject:国家自然科学基金(81230016)
Author NameAffiliationE-mail
Li Jiamei Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China  
Liu Danmeng Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China  
Zhang Xiaofeng Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China  
Qu Pengfei Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China  
Yan Hong Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China yanhonge@mail.xjtu.edu.cn 
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Abstract:
      目的 探讨陕西省农村地区育龄妇女围孕期产检次数与新生儿低出生体重(LBW)间的关系。方法 采用分层多阶段随机抽样方法,以问卷调查方式收集2010-2013年陕西省农村地区怀孕且结局明确的育龄妇女及其子女的相关信息。计数资料采用百分比描述,计量资料采用x±s描述,率的比较采用 χ2检验。将新生儿是否为LBW及围孕期产检次数分组分别作为因变量和自变量纳入广义多因素Poisson回归模型,同时控制相关混杂因素进行分析。结果 2010-2013年18 911名农村育龄妇女末次怀孕结局所生育的活产单胎新生儿中LBW发生率为3.75%。围孕期产检次数最多为15次(0.70%),最少为0次(0.70%),平均为(5.65±2.74)次;其中≥10次占12.37%,≥7次占28.52%,≥5次占62.80%,< 4次占21.49%。广义Poisson回归显示,在控制其他混杂因素后,各比较组与参照组相比,差异均有统计学意义,围孕期产检次数< 4次组新生儿LBW发生率是> 7次组的1.61倍(OR=1.61,95%CI:1.31~2.00),< 4次组是4~7次组的1.23倍(OR=1.23,95%CI:1.04~1.45)。结论 陕西省农村地区育龄妇女随着围孕期产检次数的增多,新生儿LBW发生率逐渐降低。
English Abstract:
      Objective To investigate the relationship between frequencies of prenatal care and neonatal low birth weight (LBW) among women of childbearing age from the rural areas of Shaanxi province. Methods A questionnaire survey was conducted among the childbearing-aged women from the rural areas. Samples were selected through multi stage stratified random sampling method. The childbearing aged women were in pregnancy or having had definite outcomes of pregnancy. Measurement of data was described by median±standard deviation, and chi square test was used to compare the rates. Neonatal low birth weight and frequencies of prenatal care were dependent variables and independent variables grouped into the generalized Poisson regression model. Confounding factors were under control. Results The overall incidence rate of LBW was 3.75% among 18 911 rural women of childbearing age during 2010-2013. Frequencies on pregnancy care were up to 15 times (0.70%), with a minimum of 0 (0.70%), an average of 5.65±2.74 times (including ≥10 times accounted for 12.37%; ≥7 times accounted for 28.52%; ≥5 times accounted for 62.80% and < 4 times accounted for 21.49%). After controlling confounding factors, results from the generalized Poisson regression analysis revealed that the difference was statistically significant when compared to the reference group. The incidence of neonatal LBW in the < 4 group was 1.61 times of the one in the > 7 group (OR=1.61, 95%CI:1.31-2.00) while in the < 4 group it was 1.23 times of the 4-7 group (OR=1.23, 95%CI:1.04-1.45). Conclusion In the rural areas of Shaanxi province, the incidence of neonatal LBW was gradually reduced through the increasing number of frequencies on prenatal care, among women of childbearing age.
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