| 乔晓彤,丁盈盈,何纳.HIV感染者神经认知障碍相关血液生物标志物研究[J].Chinese journal of Epidemiology,2018,39(9):1274-1280 |
| HIV感染者神经认知障碍相关血液生物标志物研究 |
| A systematic review on blood biomarkers of neurocognitive disorders in HIV infected individuals |
| Received:January 13, 2018 |
| DOI：10.3760/cma.j.issn.0254-6450.2018.09.025 |
| KeyWord: HIV 神经认知障碍 生物标志物 系统综述 |
| English Key Word: HIV Neurocognitive disorder Biomarker Systematic review |
| FundProject: |
| Author Name | Affiliation | E-mail | | Qiao Xiaotong | Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China | | | Ding Yingying | Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China | | | He Na | Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China | nhe@fudan.edu.cn |
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| Abstract: |
| 生物标志物辅助识别HIV感染者中神经认知障碍，尤其是血液中的生物标志物，凭借其操作简单、成本低、易于接受等特点，已成为更有前景的研究方向。本文系统检索了PubMed、中国知网、万方和维普数据库2008－2017年有关HIV感染者神经认知障碍的血液生物标志物研究文献，结合手工引文追溯检索到与纳入排除标准相符合的文献2篇，共纳入43篇相关文献进行系统综述，以期为深入研究和临床应用提供科学参考。 |
| English Abstract: |
| Biomarkers are very useful in the diagnosis and identification of neurocognitive impairments (NCIs) or disorders (NCDs) in HIV-infected individuals, and in particular, blood biomarkers have become more promising because they are cheap and easy to obtain or accept. A systematically literature retrieval was conducted by using PubMed, CNKI, Wanfang and VIP databases for studies about blood biomarkers of neurocognitive impairment of HIV-infected individuals in 2008-2017, according to the inclusion and exclusion criteria. Finally, a total of 43 related articles were included for this systematic review for the purpose of providing scientific evidence for further research and clinical practices. |
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