| 仇元营,王松强,王小丽,卢伟霞,乔丹,李建彬,谷园园,曾艳,陈滢,白伟志,许汴利,韩同武.一起新型冠状病毒肺炎家庭聚集性流行病学分析[J].Chinese journal of Epidemiology,2020,41(4):494-497 |
| 一起新型冠状病毒肺炎家庭聚集性流行病学分析 |
| Epidemiological analysis on a family cluster of COVID-19 |
| Received:February 21, 2020 |
| DOI：10.3760/cma.j.cn112338-20200221-00147 |
| KeyWord: 新型冠状病毒肺炎 家庭聚集性 流行病学分析 |
| English Key Word: COVID-19 Family cluster Epidemiological analysis |
| FundProject: |
| Author Name | Affiliation | E-mail | | Qiu Yuanying | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Wang Songqiang | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Wang Xiaoli | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Lu Weixia | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Qiao Dan | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Li Jianbin | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | | | Gu Yuanyuan | Jinshui Center for Disease Control and Prevention, Zhengzhou 450000, China | | | Zeng Yan | Jinshui Center for Disease Control and Prevention, Zhengzhou 450000, China | | | Chen Ying | Jinshui Center for Disease Control and Prevention, Zhengzhou 450000, China | | | Bai Weizhi | Jinshui Center for Disease Control and Prevention, Zhengzhou 450000, China | | | Xu Bianli | Henan Center for Disease Control and Prevention, Zhengzhou 450016, China | bianlixu@163.com | | Han Tongwu | Zhengzhou Center for Disease Control and Prevention, Zhengzhou 450007, China | tongwuhan@126.com |
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| Abstract: |
| 目的 针对郑州市一起新型冠状病毒肺炎(COVID-19)家庭聚集性疫情进行流行病学调查分析,探讨可能的传播模式和潜伏期传染性,为及时控制传染源、遏制疫情扩散提供科学依据。方法 采用描述性流行病学方法对8例病例进行流行病学调查分析,通过实时荧光定量PCR方法对采集的呼吸道标本进行病毒核酸检测。结果 2例具有共同武汉暴露史的病例,分别于1月31日、2月1日发病;其他6位家庭成员中1例于1月30日发病,1例于1月31日发病,3例于2月1日发病、1例于2月3日发病。结论 此次COVID-19家庭聚集性疫情,2例原发病例通过家庭共同暴露传染给其余6位家庭成员,5例续发病例发病日期早于或与原发病例同日发病,提示潜伏期具有传染性,早期居家隔离措施可能导致家庭聚集疫情风险。 |
| English Abstract: |
| Objective To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic. Methods Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of virus by RT-PCR. Results Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020. Conclusions In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19. |
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