Abstract
赵峥,李昱,牟笛,殷文武,胡健,肖霜,张俊,陈秋兰,张志杰,李中杰.2016-2018年中国重点省份境外输入性登革热病例的时空分析[J].Chinese journal of Epidemiology,2020,41(11):1808-1812
2016-2018年中国重点省份境外输入性登革热病例的时空分析
Spatial-temporal analysis on imported dengue fever in six provinces of China, 2016-2018
Received:December 31, 2019  
DOI:10.3760/cma.j.cn112338-20191231-00923
KeyWord: 登革热  输入性病例  时空分析
English Key Word: Dengue fever  Imported cases  Spatio-temporal analysis
FundProject:国家科技重大专项(2018ZX10101002-003-002);中国疾病预防控制中心应急反应机制运行项目(131031001000015001)
Author NameAffiliationE-mail
Zhao Zheng Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China  
Li Yu Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease Management, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
Mou Di Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease Management, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
Yin Wenwu Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease Management, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
Hu Jian Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China  
Xiao Shuang Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China  
Zhang Jun Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China  
Chen Qiulan Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease Management, Chinese Center for Disease Control and Prevention, Beijing 102206, China chenql@chinacdc.cn 
Zhang Zhijie Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai 200032, China zhj_zhang@fudan.edu.cn 
Li Zhongjie Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Disease Management, Chinese Center for Disease Control and Prevention, Beijing 102206, China  
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Abstract:
      目的 探讨2016-2018年中国登革热在云南省、广西壮族自治区、广东省、海南省、福建省和浙江省6个重点省份输入性病例的时空模式和流行特征。方法 收集并整理中国南部6省份2016-2018年境外输入性登革热的疫情资料,从空间、时间、人群的不同角度,分析6省份输入性登革热疫情的全球输入传播风险强度、时空动态分布以及流行病学特征。结果 中国登革热输入性病例来源于世界各地,绝大多数是东南亚地区,其中东南沿海地区的浙江省、福建省、广东省输入性病例数量多,来源广,而西南地区的云南省、广西壮族自治区和海南省则几乎局限在东南亚地区。输入性登革热病例数在这3年间逐年上升,发病高峰在8-11月,各省之间的时间聚集段稍有差别。海南省输入性病例的年龄[(37.0±19.6)岁]高于东南沿海地区[(36.0±11.7)岁]和西南地区[(32.0±16.3)岁];东南沿海地区、西南地区和海南省输入性病例的男女性别比分别为2.18:1、1.04:1和1.38:1;病例职业分布中,东南沿海地区和西南地区以商务人员为共同高发人群,此外东南沿海地区以工人、家务及待业人员为主,西南地区以农民为主,而海南省输入性病例数较少,患者分散于各职业。结论 东南沿海地区、西南地区与海南省3个地区的登革热输入模式存在差异,应在不同地区开展不同的防控措施,以实施更加精准的预防策略。
English Abstract:
      Objective To explore the spatio-temporal patterns and epidemic characteristics of imported dengue fever cases in six provinces (Yunnan, Guangxi, Guangdong, Hainan, Fujian and Zhejiang) of China from 2016 to 2018. Methods In this study, we collected the surveillance data of imported dengue fever cases from 2016 to 2018 in six southern provinces of China. The risk intensity, spatio-temporal distribution and epidemiological characteristics of imported dengue fever cases in the six provinces were analyzed from the perspective of space, time and population. Results Among the imported cases of dengue fever in China from other countries in the world, most of them were from Southeast Asia. In Zhejiang, Fujian and Guangdong provinces, there were greater number of imported cases with wide range of sources. While in Yunnan, Guangxi and Hainan provinces, the imported cases were almost from Southeast Asia. The incidence of imported dengue fever increased during the past three years, and the annual incidence peak was during August-November, but slight differences were observed among provinces. The age of the imported cases in Hainan [(37.0±19.6) years] was higher than that in southeastern coastal provinces [(36.0±11.7) years] and in southwestern provinces [(32.0±16.3) years]. The male-female ratio of the cases in southeastern coastal provinces (2.18:1) were higher than those in southwestern provinces (1.04:1) and Hainan (1.38:1). The occupations of the cases were mainly workers and unemployed people in southeastern coastal provinces and farmers in southwestern provinces, but commercial personnel was the population with high incidence in both southeastern and southwestern provinces. Less imported dengue fever cases were reported in Hainan, the population distribution varied. Conclusions There were differences in incidence pattern of imported dengue fever between southeastern coastal provinces and southwestern provinces as well as Hainan in China. Different prevention and control measures should be carried out in different areas to implement more precise prevention strategies.
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