| 王巍巍,杨智荣,周庆欣,石舒原,张格,詹思延,孙凤.COSMOS-E：病因学观察性研究的系统综述和Meta分析制作指南与案例解读[J].Chinese journal of Epidemiology,2020,41(12):2149-2159 |
| COSMOS-E：病因学观察性研究的系统综述和Meta分析制作指南与案例解读 |
| Introduction to COSMOS-E: Guidance on conducting systematic reviews and Meta-analyses on etiology of observational studies |
| Received:October 24, 2019 |
| DOI：10.3760/cma.j.cn112338-20191024-00758 |
| KeyWord: 病因学 观察性研究 系统综述 指南 |
| English Key Word: Etiology Observational study Systematic review Guidance |
| FundProject:国家自然科学基金（72074011）；北京市属医院科研培育项目（PX2019071） |
| Author Name | Affiliation | E-mail | | Wang Weiwei | The National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China | | | Yang Zhirong | Primary Care Unit, School of Clinical Medicine, University of Cambridge, Cambridge CB1 8RN, UK | | | Zhou Qingxin | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | | | Shi Shuyuan | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | | | Zhang Ge | Zhangfan Information Technology(Shanghai) Co., Ltd, Shanghai 200090, China | | | Zhan Siyan | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | | | Sun Feng | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China
Center of Evidence-based Medicine and Clinical Research, Peking University, Beijing 100191, China | sunfeng@bjmu.edu.cn |
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| Abstract: |
| 本文针对病因学观察性研究的系统综述和Meta分析制作指南（Guidance on conducting systematic reviews and Meta-analyses of observational studies of etiology，COSMOS-E）的主要内容进行了介绍，并举例说明COSMOS-E中的关键内容，内容覆盖制作病因学观察性研究系统综述的每个步骤，从提出研究问题、定义暴露和结局、评估偏倚风险到统计分析，为研究人员开展和分析这类综述提供了指导。 |
| English Abstract: |
| This paper introduces the conducting systematic reviews and Meta-analyses of observational studies of etiology (COSMOS-E) and illustrates the critical issues of COSMOS-E with a published systematic review. This document provides researchers with guidance on all steps in systematic reviews of observational studies of etiology, from shaping the research question, defining exposure and outcomes, to assessing the risk of bias and statistical analysis. |
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