Abstract
刘淼,杨姗姗,王盛书,李靖,寇福银,台朋岗,赵亚力,朱乔,甯超学,何耀.海南百岁老人糖尿病的患病率及影响因素分析[J].Chinese journal of Epidemiology,2021,42(1):68-72
海南百岁老人糖尿病的患病率及影响因素分析
Prevalence of diabetes and associated factors in Hainan centenarians
Received:April 24, 2020  
DOI:10.3760/cma.j.cn112338-20200424-00639
KeyWord: 糖尿病  空腹血糖受损  百岁老人
English Key Word: Diabetes mellitus  Impaired fasting glucose  Centenarian
FundProject:国家自然科学基金(81703285,81773502,81703308);北京市科技新星计划(Z181100006218085);解放军总医院优秀青年项目(2018-YQPY-003);解放军总医院“3+1”新秀人才项目;国家老年疾病临床医学研究中心开放课题(NCRCG-PLAGH-2017017);解放军总医院医疗大数据研发项目(2018MBD-029,MBD2018030);国家重点研发计划(2016YFC1303603,2018YFC2000400);国家科技资源共享服务平台计划(YCZYPT[2018]07)
Author NameAffiliationE-mail
Liu Miao Department of Statistics and Epidemiology, Graduate School, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China 
 
Yang Shanshan Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China  
Wang Shengshu Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China  
Li Jing Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China
Health Service Department, the Fifth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100853, China 
 
Kou Fuyin Health Service Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China  
Tai Penggang Health Service Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China  
Zhao Yali Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China  
Zhu Qiao Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China  
Ning Chaoxue Central Laboratory of Hainan Hospital, Chinese People's Liberation Army General Hospital, Sanya 572013, China  
He Yao Institute of Geriatrics, Beijing Key Laboratory of Research on Aging and Related Diseases, State Key Laboratory of Kidney Disease, National Clinical Research Center for Geriatrics Diseases, Chinese People's Liberation Army General Hospital, Beijing 100853, China yhe301@sina.com 
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Abstract:
      目的 探讨海南百岁老人糖尿病的分布特征及影响因素。方法 研究对象来自中国海南百岁老人队列研究,共1 002名百岁老人纳入分析。参考糖尿病防治指南的诊断标准,根据FPG水平和既往疾病史,将研究对象分为血糖正常组、空腹血糖受损组、糖尿病组。结果 百岁老人年龄为(102.77±2.55)岁,女性所占比例为82.0%。共有95名百岁老人患有糖尿病,糖尿病的患病率为9.5%。共有81名百岁老人患有空腹血糖受损,患病率为8.1%。百岁老人的FPG值为(5.12±1.44)mmol/L。43.5%的百岁老人FPG值集中在4.00~5.00 mmol/L,22.1%的百岁老人FPG值集中在5.00~6.00 mmol/L。TG升高和腹型肥胖可能与糖尿病患病风险有关。结论 海南百岁老人糖代谢状况优于其他年龄人群,且未呈现性别差异。
English Abstract:
      Objective To investigate basic characteristics of diabetes prevalence and associated factors in centenarians in Hainan province of China. Methods All the subjects were from China Hainan Centenarian Cohort Study. A total of 1 002 centenarians were included in the final analysis, who were divided into three groups:diabetes group, impaired fasting glucose (IFG) group, and normal glucose group according to the guideline. Results The average age of centenarians was (102.77±2.55) years, and the proportion of females was 82.0%. There were 95 centenarians who suffered from diabetes, and the prevalence rate was 9.5%. There were 81 centenarians who had IFG, and the prevalence rate was 8.1%. The mean fasting plasma glucose (FPG) level of centenarians was (5.12±1.44) mmol/L, while 43.5% of centenarians had FPG levels ranging from 4.00 to 5.00 mmol/L and 22.1% of centenarians had the FPG levels ranging from 5.00 to 6.00 mmol/L. Increased triglyceride level and abdominal obesity might be associated with the risk for diabetes. Conclusion The glycometabolism in centenarians in Hainan was better than that in other age groups, and no gender specific difference was observed.
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