| 李鑫,冯小双,张愉涵,崔宏,李霓,代敏.肺癌社区高危人群队列研究进展[J].Chinese journal of Epidemiology,2021,42(7):1174-1178 |
| 肺癌社区高危人群队列研究进展 |
| Progress in cohort study of lung cancer in high-risk population in communities |
| Received:January 18, 2021 |
| DOI：10.3760/cma.j.cn112338-20210118-00041 |
| KeyWord: 肿瘤,肺 高危人群 队列研究 |
| English Key Word: Neoplasm, lung High-risk population Cohort study |
| FundProject:国家重点研发计划（2017YFC0907900，2017YFC0907901） |
| Author Name | Affiliation | E-mail | | Li Xin | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Department of Medical Records, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou 450003, China | | | Feng Xiaoshuang | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Department of Cancer Prevention, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China | | | Zhang Yuhan | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Cui Hong | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Li Ni | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | | | Dai Min | Office of Cancer Screening, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China | daimin2002@hotmail.com |
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| Abstract: |
| 肺癌社区高危人群队列是2017年启动的国家重点研发计划精准医学专项"肺癌专病队列研究"的一部分，其主要目标是在全国7个大区的7个城市，收集5万例以上社区人群肺癌危险因素暴露信息，识别肺癌高危人群，开展低剂量螺旋CT筛查，并进一步追踪肺癌确诊和死亡信息；同时采集生物样本，建立以社区人群为基础、涵盖危险因素暴露、人群危险评估、低剂量螺旋CT筛查、生物样本以及结局随访信息的肺癌社区高危人群队列，为后续开展肺癌精准医学研究提供数据和样本支持。 |
| English Abstract: |
| The cohort study of lung cancer in high-risk population in communities in China was a part of Lung Cancer Cohort Study initiated in 2017 and funded by Precision Medicine Research of National Key Research and Development Program. Around 50 000 participants from the communities were enrolled from 7 cities in 7 regions in China. Information about the risk factors for lung cancer were collected and the populations at high risk for lung cancer were identified. Then, low-dose CT (LDCT) screening of lung cancer was conducted in the populations at high risk, and further information about the diagnosis of lung cancer cases and death cases were collected. Therefore, a community population-based cohort was established for lung cancer risk factor exposure survey, high risk population evaluation, LDCT screening and lung cancer case and death follow up. Meanwhile, biological samples were collected from all the participants in the cohort to support the future precision medicine research of lung cancer. |
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