| 张静,李秀惠,李丽,尚小飞.手足口病病原学和流行病学研究进展[J].Chinese journal of Epidemiology,2022,43(5):771-783 |
| 手足口病病原学和流行病学研究进展 |
| Etiology and epidemiology of hand, foot and mouth disease in China |
| Received:October 12, 2021 |
| DOI：10.3760/cma.j.cn112338-20211012-00788 |
| KeyWord: 手足口病 流行病学 病原学 肠道病毒 |
| English Key Word: Hand, foot, and mouth disease Epidemiology Etiology Enterovirus |
| FundProject:国家科技重大专项(2017ZX10305501004) |
| Author Name | Affiliation | E-mail | | Zhang Jing | Division of Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | | Li Xiuhui | Integrated Traditional Chinese and Western Medicine Center, Beijing Youan Hospital of Capital Medical University, Beijing 100069, China | lixiuhui@sohu.com | | Li Li | Integrated Traditional Chinese and Western Medicine Center, Beijing Youan Hospital of Capital Medical University, Beijing 100069, China | | | Shang Xiaofei | Integrated Traditional Chinese and Western Medicine Center, Beijing Youan Hospital of Capital Medical University, Beijing 100069, China | |
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| Abstract: |
| 手足口病是世界范围广泛流行的传染病，多发生于5岁以下儿童，可引起手、足、口腔等部位的皮疹和疱疹，部分重症可导致死亡，严重威胁儿童健康。肠道病毒A组71型（EV-A71）和柯萨奇病毒A组16型（CV-A16）等EV是引起我国手足口病持续流行的主要病因。2013年以后，其他EV在手足口病病例中所占比例逐渐增多，引起重症和死亡病例。本文对2008年以来我国手足口病流行病学和病原学的主要研究进展进行综述。 |
| English Abstract: |
| Hand, foot and mouth disease (HFMD) has been widespread in the world, and caused fever, rashes and other clinical symptoms of children, and sometimes inducing respiratory failure, brainstem encephalitis, and other complications, even death. The disease is mainly caused by enterovirus 71 (EV-A71) and coxsackievirus 16 (CV-A16). Since 2013, the proportion of HFMD cases caused by other enteroriruses has gradually increased, causing severe and even fatal cases. This paper summarizes the research progress in the epidemiological and etiological characteristics of HFMD in China since 2008. |
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