Abstract
徐伟,邢秀雅,许精巧,曹丹,贺琴,戴丹,贾尚春,程倩瑶,吕逸丽,张鸾,梁岭,谢国蝶,陈叶纪,王华东,刘志荣.安徽省成年居民慢性肾病患病流行现状及相关因素研究[J].Chinese journal of Epidemiology,2022,43(11):1717-1723
安徽省成年居民慢性肾病患病流行现状及相关因素研究
A cross-sectional study of prevalence of chronic kidney disease and related factors in adults in Anhui province
Received:March 14, 2022  
DOI:10.3760/cma.j.cn112338-20220314-00185
KeyWord: 慢性肾病  成年居民  危险因素  横断面调查
English Key Word: Chronic kidney disease  Adult residents  Risk factors  Cross-sectional study
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Author NameAffiliationE-mail
Xu Wei Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Xing Xiuya Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Xu Jingqiao Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Cao Dan Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
He Qin Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Dai Dan Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Jia Shangchun Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Cheng Qianyao Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Lyu Yili Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Zhang Luan Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Liang Ling Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Xie Guodie Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Chen Yeji Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Wang Huadong Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China  
Liu Zhirong Department of Chronic Non-communicable Diseases, Anhui Provincial Center for Disease Control and Prevention/Public Health Research Institute of Anhui Provincial, Hefei 230601, China liuzhirong66@126.com 
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Abstract:
      目的 利用2018年安徽省中国成人慢性病与营养监测数据,比较不同特征成年居民慢性肾病(CKD)患病率,并分析其相关因素。方法 采用多阶段分层整群随机抽样方法,选取≥18岁居民进行询问调查、身体测量和实验室检测。使用复杂加权方法估算不同特征居民的CKD患病率,CKD患病及其相关因素的多因素分析采用复杂抽样数据logistic回归模型。结果 共纳入7 181人,成年居民CKD患病率为11.06%,女性CKD患病率(12.49%)高于男性(9.59%),差异有统计学意义(P<0.05)。居民CKD进展的中、高和极高风险程度比例分别为8.66%、2.02%和0.38%。多因素分析结果显示,年龄(OR=1.03,95%CI:1.00~1.05)和BMI(OR=1.05,95%CI:1.01~1.09)增加、女性(OR=1.38,95%CI:1.22~1.55)、高血压(OR=2.50,95%CI:1.76~3.56)、糖尿病(OR=2.28,95%CI:1.51~3.43)、血脂异常(OR=1.26,95%CI:1.11~1.43)和高尿酸血症(OR=2.16,95%CI:1.68~2.78)均为CKD的危险因素。结论 安徽省成年居民CKD患病率较高,CKD与年龄、性别、BMI、高血压、糖尿病、血脂异常和高尿酸血症相关,应当注重相关危险因素的管控,包括超重/肥胖、高血压、糖尿病、血脂异常和高尿酸血症,预防CKD及其并发症。
English Abstract:
      Objective To understand the prevalence of chronic kidney disease (CKD) and related factors in adults in Anhui province based on the data of Chinese Chronic Diseases and Nutrition Surveillance program (2018) in Anhui. Methods Multi-stage stratified cluster random sampling was used to select participants aged ≥ 18 years. Moreover, questionnaire survey, body measurements and laboratory tests were conducted. The complex weighting method was used to estimate the prevalence of CKD in residents with different characteristics, and complex sampling data logistic regression model was used for multivariate analysis to identify related risk factors. Results A total of 7 181 participants were included. The overall prevalence of CKD was 11.06% in adults in Anhui, and the prevalence was 12.49% in women and 9.59% in men (P<0.05). The moderate, high and very high risk for CKD progression were 8.66%, 2.02% and 0.38%, respectively. Multivariate analysis showed that age (OR=1.03, 95%CI:1.00-1.05), BMI (OR=1.05, 95%CI:1.01-1.09), being woman (OR=1.38,95%CI:1.22-1.55), hypertension (OR=2.50, 95%CI:1.76-3.56), diabetes (OR=2.28, 95%CI:1.51-3.43), dyslipidemia (OR=1.26, 95%CI:1.11-1.43) and hyperuricemia (OR=2.16, 95%CI:1.68-2.78) were risk factors for CKD. Conclusion The prevalence of CKD in adults in Anhui was relatively high and age, gender, BMI, hypertension, diabetes, dyslipidemia and hyperuricemia were found to be associated with the prevalence of CKD. To prevent CKD and its complications, attention should be paid to the management of related risk factors, including overweight and obesity, hypertension, diabetes, dyslipidemia and hyperuricemia.
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