| 周荣飞,朱珍妮,汪正园,臧嘉捷,贾晓东,吕筠,李立明,吴凡.上海市成年双生子健康生活方式与肥胖的关联研究[J].Chinese journal of Epidemiology,2023,44(6):862-867 |
| 上海市成年双生子健康生活方式与肥胖的关联研究 |
| A case-control study on the association between a healthy lifestyle and obesity among adult twins in Shanghai |
| Received:November 14, 2022 |
| DOI：10.3760/cma.j.cn112338-20221114-00970 |
| KeyWord: 超重 肥胖 双生子 病例对照研究 |
| English Key Word: Overweight Obesity Twins Case-control study |
| FundProject:卫生行业科研专项（201502006，201002007） |
| Author Name | Affiliation | E-mail | | Zhou Rongfei | School of Public Health, Fudan University, Shanghai 200032, China | | | Zhu Zhenni | Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China | | | Wang Zhengyuan | Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China | | | Zang Jiajie | Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China | | | Jia Xiaodong | Shanghai Chemical Industry Park Medical Center, Shanghai 201507, China | | | Lyu Jun | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | | | Li Liming | Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China | | | Wu Fan | School of Public Health, Fudan University, Shanghai 200032, China | wufan@shmu.edu.cn |
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| Abstract: |
| 目的 分析上海市成年双生子健康生活方式的数量与超重/肥胖及腹型肥胖的关联。方法 使用2017-2018年上海市双生子项目第二轮调查数据，通过病例对照的研究设计分析健康生活方式与肥胖的关联，并进一步利用双生子配对控制遗传等混杂因素。结果 共纳入7 864名（3 932对）成年双生子。同卵双生子配对病例对照分析显示，与0~2种健康生活方式者相比，有3种和4~5种健康生活方式者患超重/肥胖的风险分别降低49%（OR=0.51，95%CI：0.28~0.93）和70%（OR=0.30，95%CI：0.13~0.69），患腹型肥胖的风险分别降低17%（OR=0.83，95%CI：0.44~1.57）和66%（OR=0.34，95%CI：0.14~0.80）；并且每增加1种健康生活方式，患超重/肥胖的风险降低41%（OR=0.59，95%CI：0.42~0.85），患腹型肥胖的风险降低37%（OR=0.63，95%CI：0.44~0.90）。结论 健康生活方式的数量与超重/肥胖及腹型肥胖均相关，数量越多，患病风险越低。 |
| English Abstract: |
| Objective To investigate the associations between the numbers of healthy lifestyles and overweight/obesity and abdominal obesity in adult twins in Shanghai. Methods Based on the Shanghai Twin Registry System Phase Ⅱ survey data in 2017-2018, a case-control study was conducted to analyze the association between healthy lifestyles and obesity and further adjusted for confounders by a co-twin control study. Results A total of 7 864 adult twins (3 932 pairs) were included. In the co-twin case-control analysis for monozygotic twins, compared with participants with 0 to 2 healthy lifestyles, those with 3 and 4 to 5 healthy lifestyles had a 49% (OR=0.51, 95%CI: 0.28-0.93) and 70% (OR=0.30, 95%CI: 0.13-0.69) lower risk of overweight/obesity, respectively, and a 17% (OR=0.83, 95%CI: 0.44-1.57) and 66% (OR=0.34, 95%CI: 0.14-0.80) lower risk of abdominal obesity, respectively. For each additional healthy lifestyle, the risk of developing overweight/obesity was reduced by 41% (OR=0.59, 95%CI: 0.42-0.85), and the risk of developing abdominal obesity was reduced by 37% (OR=0.63, 95%CI: 0.44-0.90). Conclusion An increasing number of healthy lifestyles was associated with a marked decreased risk for both overweight/obesity and abdominal obesity. |
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