| 沈丹洋,马爱娟,董忠.北京市成年居民二手烟暴露与血脂异常的关系研究[J].Chinese journal of Epidemiology,2023,44(6):924-930 |
| 北京市成年居民二手烟暴露与血脂异常的关系研究 |
| Study on the relationship between secondhand smoke exposure and dyslipidemia in adult residents in Beijing |
| Received:September 29, 2022 |
| DOI：10.3760/cma.j.cn112338-20220929-00828 |
| KeyWord: 二手烟暴露 血脂异常 成年人 监测 |
| English Key Word: Secondhand exposure Dyslipidemia Adults Surveillance |
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| Abstract: |
| 目的 了解北京市成年人二手烟暴露和血脂异常的关系，为开展相关干预提供科学依据。方法 本研究利用北京市2017年成人慢性病及其危险因素监测的数据。采用多阶段分层整群抽样方法在全市范围内抽取调查对象13 240人。监测内容包括问卷调查、体格测量、采集空腹静脉血进行相关生化指标测定。采用SPSS 20.0软件进行χ2检验及多因素logistic回归分析。结果 每天暴露于二手烟者总血脂异常患病率（39.27%）、高TG血症患病率（22.61%）、高LDL-C血症患病率（6.03%）均为最高，在男性调查对象中，每天暴露于二手烟者的总血脂异常患病率（44.42%）、高TG血症患病率（26.12%）最高。调整混杂因素后的多因素logistic回归分析显示，与无二手烟暴露相比，暴露频率为平均1~3 d/周的人群总血脂异常患病风险最高（OR=1.276，95%CI：1.023~1.591）。高TG血症中，每天暴露二手烟人群患病风险最高（OR=1.356，95%CI：1.107~1.661）。在男性中，二手烟暴露频率为平均1~3 d/周者患总血脂异常的风险较高（OR=1.366，95%CI：1.019~1.831），患高TG血症的风险最高（OR=1.377，95%CI：1.058~1.793）。女性的二手烟暴露频率和血脂异常患病风险之间的关联性无统计学意义。结论 北京市成年人尤其是男性有二手烟暴露会增加总血脂异常，尤其是高TG血症的患病风险，需要提高个人健康意识，尽量减少或避免二手烟暴露。 |
| English Abstract: |
| Objective To understand the relationship between secondhand smoke exposure and dyslipidemia among adults in Beijing and to provide a scientific basis for relevant intervention. Methods Data were from Beijing Adult Non-communicable and Chronic Diseases and Risk Factors Surveillance Program in 2017. A total of 13 240 respondents were selected by multistage cluster stratified sampling method. The monitoring contents include a questionnaire survey, physical measurement, collection of fasting venous blood, and determination of related biochemical indicators. SPSS 20.0 software was used for the chi-square test and multivariate logistic regression analysis. Results The prevalence of total dyslipidemia (39.27%), hypertriglyceridemia (22.61%), and high LDL-C (6.03%) were the highest among those exposed to daily secondhand smoke. Among the male respondents, the prevalence of total dyslipidemia (44.42%) and hypertriglyceridemia (26.12%) were the highest among those exposed to secondhand smoke daily. Multivariate logistic regression analysis after adjustment for confounding factors showed that compared with no exposure to secondhand smoke, the population with an average exposure frequency of 1-3 days per week had the highest risk of total dyslipidemia (OR=1.276, 95%CI: 1.023-1.591). Among the patients with hypertriglyceridemia, those exposed to secondhand smoke daily had the highest risk (OR=1.356, 95%CI: 1.107-1.661). Among the male respondents, those exposed to secondhand smoke for 1-3 days per week had a higher risk of total dyslipidemia (OR=1.366, 95%CI: 1.019-1.831), and the highest risk of hypertriglyceridemia (OR=1.377, 95%CI: 1.058-1.793). There was no significant correlation between the frequency of secondhand smoke exposure and the risk of dyslipidemia among female respondents. Conclusions Secondhand smoke exposure in Beijing adults, especially men, will increase the risk of total dyslipidemia, especially hyperlipidemia. Improving personal health awareness and minimizing or avoiding exposure to secondhand smoke is necessary. |
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