| 张晓楠,焦珂笛,苏生利,廖玫珍,马伟.基于潜在剖面分析的男男性行为人群HIV感染者生存质量及相关因素研究[J].Chinese journal of Epidemiology,2023,44(8):1290-1295 |
| 基于潜在剖面分析的男男性行为人群HIV感染者生存质量及相关因素研究 |
| A study on quality of life and related factors among HIV-infected men who have sex with men based on latent profile analysis |
| Received:November 30, 2022 |
| DOI：10.3760/cma.j.cn112338-20221130-01023 |
| KeyWord: 艾滋病 男男性行为者 生存质量 潜在剖面分析 |
| English Key Word: AIDS Men who have sex with men Quality of life Latent profile analysis |
| FundProject:国家重点研发计划（2017YFE0103800）；山东省医药卫生科技发展计划（2019WS430） |
| Author Name | Affiliation | E-mail | | Zhang Xiaonan | Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Ji'nan 250012, China | | | Jiao Kedi | Vanke School of Public Health, Tsinghua University, Beijing 100084, China | | | Su Shengli | Department of AIDS/STD Control and Prevention, Shandong Center for Disease Control and Prevention, Ji'nan 250014, China | | | Liao Meizhen | Department of AIDS/STD Control and Prevention, Shandong Center for Disease Control and Prevention, Ji'nan 250014, China | liaomz161@126.com | | Ma Wei | Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Ji'nan 250012, China | weima@sdu.edu.cn |
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| Abstract: |
| 目的 探讨MSM HIV感染者(MSM感染者)生存质量情况的潜在分类,并分析不同类别的可能影响因素。方法 对2020年10-12月在山东省济南市某传染病医院接受抗病毒治疗的MSM感染者进行问卷调查。将感染者在6个领域的生存质量得分进行潜在剖面分析,并通过有序logistic回归分析探索潜在分类的相关因素。结果 研究对象MSM感染者共584人。潜在剖面分析将MSM感染者的生存质量划分为3类(得分较低组、得分中等组和得分较高组),分别占34.4%(201/584)、49.8%(291/584)和15.8%(92/584)。多因素有序logistic回归分析结果显示,年龄>40岁(aOR=1.77,95%CI:1.11~2.80)、月均收入 ≤ 3 000元(aOR=3.15,95%CI:1.72~5.76)、月均收入3 001~5 000元(aOR=2.26,95%CI:1.41~3.62)、到医院取药的距离>40 km(aOR=1.76,95%CI:1.07~2.89)和服用药物后出现不良反应(aOR=2.31,95%CI:1.65~3.23)是生存质量得分较低的相关因素。结论 MSM感染者的生存质量存在群体异质性,且处于较高水平。应重点关注年龄较大、经济收入较低、距诊疗服务点较远的MSM感染者。减少抗病毒治疗药物的不良反应,提高生存质量。 |
| English Abstract: |
| Objectives To investigate the potential classification of quality of life in HIV-infected men who have sex with men (HIV-infected MSM) and to analyze possible influencing factors of different categories. Methods A questionnaire survey was conducted among HIV-infected MSM who received antiretroviral treatment (ART) in an infectious disease hospital in Ji'nan, Shandong Province from October to December 2020. The quality of life scores in six domains were analyzed by latent profile analysis (LPA), and possible related factors of potential classification were explored by ordinal logistic regression analysis. Results A total of 584 HIV-infected MSM were included in this study. LPA divided their quality of life into three categories, named low score, medium score and high score groups, accounting for 34.4% (201/584), 49.8% (291/584), and 15.8% (92/584), respectively. Multivariate ordinal logistic regression analysis showed that age above 40 years (aOR=1.77, 95%CI:1.11-2.80), monthly average income of 3 000 Yuan and below (aOR=3.15, 95%CI:1.72-5.76), monthly average income of 3 001-5 000 Yuan (aOR=2.26, 95%CI:1.41-3.62), distance to the hospital to receive drugs farer than 40 kms (aOR=1.76, 95%CI:1.07-2.89), and adverse reactions after taking drugs (aOR=2.31, 95%CI:1.65-3.23) were factors associated with low level of quality of life. Conclusions The qualities of life of HIV-infected MSM showed group heterogeneity and were at high levels. Attention should be focused on HIV-infected MSM who are at older age, with low income, and long distance to access the health facilities. The measures should be taken to reduce the adverse reactions of ART drugs and improve the quality of life. |
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