文章摘要
李洪星,金宝相,廖建岗,尹建强,熊化保.红细胞膜Na+泵缺陷与原发性高血压:多元条件Logistic回归分析[J].中华流行病学杂志,1989,10(2):98-101
红细胞膜Na+泵缺陷与原发性高血压:多元条件Logistic回归分析
A Study on the Relationship between Reduced Activity of Red Cell Membrane Sodium-Potassium Pump and Essential Hypertension
收稿日期:  出版日期:2021-06-01
DOI:
中文关键词: 原发性高血压  红细胞膜Na+  条件Logistic回归分析
英文关键词: Essential hypertension  Red cell membrame sodium potassium pump  Conditional logistic regression
基金项目:
作者单位
李洪星 南京铁道医学院卫生系 
金宝相 南京铁道医学院卫生系 
廖建岗 南京铁道医学院卫生系 
尹建强 南京铁道医学院卫生系 
熊化保 南京铁道医学院卫生系 
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中文摘要:
      1986年在某工厂对红细胞膜Na+泵缺陷与原发性高血压的关系进行了103对配比调查。资料分析采用了条件Logistic回归分析方法。本研究提示RBCNa+的增高,RBCK+及RBCNa+,K+ATP-ase活性的降低与高血压有显著的联系;血浆Na+与体重这两个高血压的重要危险因素均与RBCNa+,K+ATPase活性的降低有关,提出红细胞膜的Na+泵功能缺陷可能是这两个因素对高血压的共同作用环节。
英文摘要:
      A population-based matched study of 103 pairs on the relation of sodium-potassium pump defect and hypertension was conducted at a factory in 1986.Conditional Logistic regression technique was used in data analysis.It was suggested that the increase of RBCNa+ and decrease of RBCK+ and RBCNa+, K+ ATP-ase were significantly associated with hypertension.Plasma sodium and body weight. which were considered as important risk factors of hypertension, were fund correlated with the decrease of RBCNa+, K+ ATPase, it was proposed that reduced activity of cell membrane sodium-potassium pump might be the common link of the two factors with hypertension.
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