| 程立法,王敏峥,杨文秀.不孕症危险因素的病例对照研究[J].中华流行病学杂志,1991,12(4):217-221 |
| 不孕症危险因素的病例对照研究 |
| A Case-Control Study of Dangerous Factors Related to Infertility |
| 收稿日期:1990-07-02 出版日期:2021-06-07 |
| DOI： |
| 中文关键词: 不孕症 危险因素 病例对照研究 |
| 英文关键词: Infertility Dangerous factors Case-control study |
| 基金项目: |
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| 摘要点击次数: 1266 |
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| 中文摘要: |
| 1987~1988年在河南省进行了不孕症危险因素病例对照研究。调查资料采用单因素分析、Logistic逐步回归多因素分析。单因素分析结果提示,男性不育的危险因素为:食用粗制棉油、精索静脉曲张、鞘膜积液、性发育异常、阴毛分布异常、青春期遗尿、青春后期腮腺炎、家族不育史和高温下作业等。与女方不孕有密切关系的因素为月经异常、性交频度过低和性交痛、家族不孕史、TB病史及其它慢性疾病等。多因素Logistic逐步回归分析结果:男方不育危险因素依次为食用粗制棉油、精索静脉曲张、性发育异常和青春期遗尿;女方为月经异常、TB病史;夫妇双方共同因素为近亲结婚、性交频度过低、夫妇任何一方经常接触有害物质等。多因素Logistic回归分析和单因素分析结果不完全一致是因为Logistic回归分析既考虑了各因素的主要效应,也考虑了有关因素的综合作用,所以更接近客观实际。 |
| 英文摘要: |
This paper reports the case-control study of dangerous factors related to infertility in Henan province during 1987~1988.
There were two groups. One was a primary infertility group with 319 couples. The other was a normal fertility gruop with 714 couples, who were neighboars of the first group, among whom the women's age range was within 6 years old.
The survey materials were analized by SAS programmes in the computer. The methods of analysis were single factor and logistic regression analysis of factors.
The results of single factor analysis showed that in male, infertility had aclose relationship with eating edible rude cotton seed oil; suffering from Varicocele; hydrocele of tunica vaginalis; sex dysplasia; breast dyslasia; puberty enuresis; parotitis after puberty; familial infertility and working under high temperature coudilions. In female, menstrual disorder; asexuality or pain during coitus; familial infertility; TB and other chronic diseases might be major contributors to the incidence of infertility.
The results of logistic regression analysis of the factors related to infertility suggested that in male, eating edible rude cotton seed oil, suffering form varicocele; sex dysplasia; puberty enuresis; and in female, menstrual disorder; TB; consanguineous marriage, lower rate of coitus, freguent contact with pernicious substances might be major dangerous factors causing infertility.
The results of the logistic regression analysis were different from those of the single factor analysis because the former not only analyzed the major influence of each factor but also consilerel the comprehensive effects of the relevant factors. |
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