文章摘要
顾云娟,贾伟平.降糖药物与恶性肿瘤关系的研究进展[J].中华流行病学杂志,2011,32(11):1170-1173
降糖药物与恶性肿瘤关系的研究进展
The relationship of antidiabetic drugs and cancer risk
收稿日期:2011-05-16  出版日期:2014-09-18
DOI:
中文关键词: 糖尿病;恶性肿瘤;降糖药物
英文关键词: Diabetes;Neoplasms;Antidiabetic drugs
基金项目:上海市科学计划委员会重大项目(09DZ1950202)
作者单位E-mail
顾云娟,贾伟平 上海交通大学附属第六人民医院内分泌代谢科上海市糖尿病研究所上海市糖尿病重点实验室上海市糖尿病临床医学中心 200233
南通大学附属医院内分泌代谢科 
wpjia@yahoo.com 
摘要点击次数: 1652
全文下载次数: 1158
中文摘要:
      有研究认为糖尿病与某些肿瘤的发生相关。而长期的糖尿病病程中各种降糖药的使用是否也参与其中,目前还不明确
英文摘要:
      objective To analyze the risk factors related to survival time of advanced non- small cell lung cancer(NSCLC)and to establish a prediction model on survival time.Methods From 2004-2006.1 84 patients with advanced NSCLC were enrolled in the Affiliated Hospital to the Nantong Midical College.Related risk factors were analyzed.using the Buckley-James model.Both actual and predicted survival time were compared by log.rank test.Results Through Buckley-James model analysis,data showed that loS,clinical stage,treatment and pre-treatment hemoglobin were main influencing factors on survival time.Regression equation appeared to be InMONTH= 0.0108 KPS+0.0238 HB+0.4614 IIIb+0.8027Ⅲa+0.3869(radiotherapy+chemotherapy)+0.507 (radiotherapy+operation)+0.6082(chemotherapy+operation)一2.098.There was no statistical difference between the prediction and the actual models of survival time by log-rank test(P----0.575> O.05).Conclusion KPS,clinical stage,treatment and pre.treatment hemoglobin might be associated. Both the prognosis of patients with advanced NSCLC and the prediction model seemed to have practical signiflcances.
查看全文   Html全文     查看/发表评论  下载PDF阅读器
关闭