| 邱涛,丁萍,刘晓燕,徐金水,郭宏雄,傅更锋,徐晓琴,还锡萍.江苏省2005－2013年首次接受抗病毒治疗的HIV/AIDS流行病学特征分析[J].中华流行病学杂志,2014,35(12):1320-1323 |
| 江苏省2005－2013年首次接受抗病毒治疗的HIV/AIDS流行病学特征分析 |
| Epidemiological characteristics of HIV/AIDS patients newly received highly active antiretroviral therapy during 2005-2013 in Jiangsu province |
| 收稿日期:2014-06-30 出版日期:2014-12-10 |
| DOI：10.3760/cma.j.issn.0254-6450.2014.12.002 |
| 中文关键词: 高效抗反转录病毒治疗 获得性免疫缺陷综合征 人类免疫缺陷病毒 |
| 英文关键词: Highly active antiretroviral therapy Acquired immunodeficiency syndrome Human immunodeficiency virus |
| 基金项目:国家科技重大专项(2013ZX10004-905) |
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| 中文摘要: |
| 目的 了解2005－2013年江苏省首次入组艾滋病免费抗病毒治疗HIV/AIDS的流行病学特征.方法 收集2005－2013年江苏省首次接受抗病毒治疗的HIV/AIDS入组时基本资料,建立Excel数据库并用SPSS 16.0软件进行分析.结果 2005－2013年江苏省首次入组治疗HIV/AIDS共5 788人,新治疗人数逐年增多.79.7%为江苏省籍,性别比为4.69:1,平均年龄为(39.9±12.6)岁,已婚者占55.8%.在疾病预防控制中心治疗者占52.0%.感染途径主要为男男性传播和异性性传播(91.9%),入组时基线CD4+T淋巴细胞计数平均为187 cell/μl.开始治疗时间与确证时间间隔M为4.0个月.男性、>59岁、未婚、外省籍、在医院治疗和高基线CD4+T淋巴细胞的比例有逐年上升趋势.结论 江苏省HIV/AIDS开始抗病毒治疗时机有所提前,但仍有大部分HIV/AIDS治疗较晚,其HIV阳性发现较晚是主要原因,HIV感染者早发现能力仍需加强. |
| 英文摘要: |
| Objective To analyze the epidemiological characteristics of the HIV/AIDS patients newly received highly active antiretroviral therapy(HAART) during 2005-2013 in Jiangsu province. Methods According to the baseline data of HIV/AIDS patients newly received HAART during 2005-2013,an Excel database was established and statistical analysis was performed using SPSS 16.0 software. Results There were 5 788 HIV/AIDS patients newly received HAART during 2005-2013 and the number increased annually. 79.7% of these patients were from the local province,with the ratio of male to female as 4.69:1,mean age as 39.9 years old,55.8% of them married,52.0% of them were treated at CDC. 91.9% of them were infected through sexual contacts. Mean baseline CD4+T cell count of cases was 187 cells/μl. Median of the interval between the time of HIV confirmation and HAART initiation was 4.0 months. Proportion of the HIV/AIDS patients that were being male, elderly, unmarried, not local resident,treated in hospitals and with higher baseline CD4+T count etc. showed a trend of increase. Conclusion HIV/AIDS patients had the opportunity to start the HAART at early stage of the disease. However,many of them started the treafment late as the results of being diagnosed late. Programs related to both earlier detection and diagnosis on HIV cases should be strengthened. |
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