文章摘要
李世明,冯为,方芳,董小惠,张紫娟,杨雀屏.中国儿童注意缺陷多动障碍患病率Meta分析[J].中华流行病学杂志,2018,39(7):993-998
中国儿童注意缺陷多动障碍患病率Meta分析
Prevalence of attention deficit and hyperactivity disorder in children in China: a systematic review and Meta-analysis
投稿时间:2017-11-16  
DOI:10.3760/cma.j.issn.0254-6450.2018.07.024
中文关键词: 注意缺陷多动障碍;儿童;患病率;Meta分析
英文关键词: Attention deficit and hyperactivity disorder;Children;Prevalence;Meta-analysis
基金项目:
作者单位E-mail
李世明 214000 南京医科大学附属无锡精神卫生中心社会防治办公室  
冯为 214000 南京医科大学附属无锡精神卫生中心社会防治办公室  
方芳 214000 南京医科大学附属无锡精神卫生中心社会防治办公室  
董小惠 214000 南京医科大学附属无锡精神卫生中心社会防治办公室  
张紫娟 214000 南京医科大学附属无锡精神卫生中心社会防治办公室  
杨雀屏 214000 南京医科大学附属无锡精神卫生中心社会防治办公室 cj183304090@126.com 
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中文摘要:
      目的 通过Meta分析了解我国儿童注意缺陷多动障碍(ADHD)患病情况,为早期防治提供科学依据。方法 检索1979-2017年中国期刊全文数据库(CNKI)、万方数据库(Wanfang data)、中国生物医学文献数据库(CBM)、维普数据库(VIP)中有关中国儿童ADHD患病率研究文献,检索1946-2017年PubMed中研究地区在中国的相关文献。根据STROBE声明中横断面研究评价标准进行文献质量评价,利用Stata 12.0软件合并患病率,并对性别、地区、发表年份、诊断方法及抽样方法等因素进行亚组分析,采用Egger检验及漏斗图评估各文献发表偏倚,通过采用不同模型和排除其中任意1篇文献对合并效应值的影响进行敏感性分析。结果 共纳入20篇文献,总样本量88 755人,男童46 216人,女童42 539人。中国儿童ADHD总患病率为5.6%(95% CI:5.0%~6.3%)。亚组分析显示男童患病率7.7%(95% CI:6.7%~8.8%),女童患病率3.4%(95% CI:3.0%~3.8%),差异有统计学意义(P<0.05)。不同地区、发表年代、诊断方法和抽样方法之间差异无统计学意义。结论 我国儿童ADHD患病率较高,男童患病率明显高于女童,应采取早筛查、早治疗方案并进行相应干预。
英文摘要:
      Objective To understand the prevalence of attention deficit and hyperactivity disorder (ADHD) in children in China and provide scientific basis for early prevention and treatment of ADHD in children. Methods A systematic literature retrieval was conducted by using CNKI, Wanfang data, CBM and VIP databases for the information about the prevalence of ADHD in children in China published from 1979 to 2017. Pubmed database was used to retrieve the literatures about ADHD prevalence in children in China published from 1946 to 2017. The quality of literature was evaluated based on the cross-sectional study criteria according to STROBE statement. Stata 12.0 was used for combined prevalence and subgroup analyses, including gender, regions, publication year, diagnostic criteria, sampling methods, and so on. Egger testing and the evaluation of funnel graph were used to evaluate the publication bias of these literatures, and sensitivity analysis was done by using different models and eliminating the influence of any one of these articles on combined effect value. Results Twenty articles were included. The total sample size was 88 755, including 46 216 boys and 42 539 girls. The prevalence of ADHD in children in China was 5.6% (95%CI:5.0%-6.3%). The prevalence was 7.7% (95%CI:6.7%-8.8%) in boys and 3.4% (95%CI:3.0%-3.8%) in girls, the difference was statistically significant (P<0.05). No statistically significance difference in the ADHD prevalence was observed between different regions publication years, diagnostic criteria and sampling methods. Conclusions The prevalence of ADHD in children in China was high, and boys tended to have a higher prevalence compared with girls. Appropriate screening methods for early detection and intervention conduction of ADHD should be taken among children in China.
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