文章摘要
陈江天,王翠娥,潘晓红,俞丽,蒋均,孙淼军.杭州市2008-2017年无偿献血者HIV感染状况及特征分析[J].中华流行病学杂志,2019,40(3):322-326
杭州市2008-2017年无偿献血者HIV感染状况及特征分析
HIV infection status and characteristics of non-remunerated blood donors in Hangzhou, 2008-2017
投稿时间:2018-10-25  
DOI:10.3760/cma.j.issn.0254-6450.2019.03.012
中文关键词: 无偿献血者;艾滋病病毒;感染
英文关键词: Non-remunerated blood donors;HIV;Infection
基金项目:2019年浙江省医药卫生科技计划(2019KY066)
作者单位E-mail
陈江天 浙江省血液中心, 杭州 310052  
王翠娥 浙江省血液中心, 杭州 310052  
潘晓红 浙江省疾病预防控制中心, 杭州 310051  
俞丽 浙江省血液中心, 杭州 310052  
蒋均 浙江省疾病预防控制中心, 杭州 310051 jjiang@cdc.zj.cn 
孙淼军 浙江省血液中心, 杭州 310052 smjatt@163.com 
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中文摘要:
      目的 了解浙江省杭州市无偿献血者的HIV感染状况及流行特征,为经输血传播艾滋病防控工作提供参考依据。方法 收集和分析2008-2017年杭州市无偿献血者献血资料,无偿献血者的HIV阳性率分为粗阳性率和标化阳性率,采用趋势χ2检验法描述无偿献血者的HIV感染状况、流行特征及变化趋势。结果 2008-2017年杭州市无偿献血者1 461 129人中,发现HIV感染者260例,以男性(96.5%,251/260)、18~34岁(72.7%,189/260)为主,重复无偿献血者占36.9%(96/260),传播途径为异性性行为、男男性行为分别为44.6%(116/260)、53.5%(139/260)。MSM人群HIV感染者中,以18~34岁(82.0%,114/139)、未婚(71.2%,99/139)为主。学生人群HIV感染者,以男男性行为感染为主(88.4%,23/26)。2008-2017年HIV粗阳性率为0.8/万~2.5/万,各年的差异无统计学意义(趋势χ2=2.355,P=0.125);18~24岁男性HIV粗阳性率从2008年的1.1/万上升到2017年的3.7/万,差异有统计学意义(趋势χ2=5.175,P=0.023)。2008-2017年HIV标化阳性率为0.9/万~2.4/万。结论 2008-2017年杭州市无偿献血者HIV感染状况呈低流行水平,HIV感染者以男性、18~34岁、传播途径以异性性行为和男男性行为为主,18~24岁男性HIV阳性率呈上升趋势。
英文摘要:
      Objective To understand HIV infection status and characteristics of non-remunerated blood donors in Hangzhou. Methods HIV antibody test were conducted for non-remunerated blood donors in Hangzhou and their demographic and epidemiological information were collected from 2008-2017. χ2 test for trend (liner by liner association chi square test) was used for the comparison of the HIV infection trends in each year. Results A total of 1 461 129 non-remunerated blood donors were surveyed in Hangzhou during 2008-2017, and 260 blood donors were HIV positive. Most HIV infected blood donors were males (96.5%, 251/260) and aged 18-34 years (72.7%, 189/260). Among 260 HIV positive blood donors, those reporting repeated non-remunerated blood donation accounted for 36.9% (96/260), those reporting homosexual transmission accounted for 53.5% (139/260) and those reporting heterosexual transmission accounted for 44.6% (116/260). The HIV infected persons reporting homosexual behaviors were mainly aged 18-34 years (82.0%, 114/139) and unmarried (71.2%, 99/139). Most HIV infected students reported homosexual transmission (88.4%, 23/26). The crude HIV positive rate was 0.8/10 000-2.5/10 000, the differences in annual HIV positive rate had no significance (trend χ2=2.355, P=0.125). The crude HIV positive rate in male blood donors aged 18-24 years increased from 1.1/10 000 in 2008 to 3.7/10 000 in 2017, the difference was significant (trend χ2=5.175, P=0.023). Standardized HIV positive rate was 0.9/10 000-2.4/10 000. Conclusions HIV infection rate was low in non-remunerated blood donors in Hangzhou during 2008-2017. Most HIV infected persons were males and aged 18-34 years. Heterosexual and homosexual contacts were the major transmission routes. The HIV positive rate in males aged 18-24 years showed an increase trend.
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