文章摘要
王旭明,黄梅会,崔步云.海南省布鲁氏菌病疫情特征研究[J].中华流行病学杂志,2019,40(3):350-353
海南省布鲁氏菌病疫情特征研究
Analysis on brucellosis epidemiological characteristics in Hainan province
投稿时间:2018-09-09  
DOI:10.3760/cma.j.issn.0254-6450.2019.03.018
中文关键词: 布鲁氏菌;种型鉴定;流行病学
英文关键词: Brucella;Species identification;Epidemiology
基金项目:
作者单位E-mail
王旭明 海南省人民医院检验科, 海口 570311  
黄梅会 海南省人民医院检验科, 海口 570311  
崔步云 中国疾病预防控制中心传染病预防控制所 感染性疾病诊治协同创新中心 传染病预防控制国家重点实验室, 北京 102206
内蒙古自治区布鲁氏菌病防治技术研究中心, 通辽 028000 
cuibuyun@icdc.cn 
摘要点击次数: 441
全文下载次数: 277
中文摘要:
      目的 分析海南省布鲁氏菌病(布病)流行病学特征。方法 对2012-2017年海南省收集的16株布鲁氏菌采用Vitek 2 compact进行布鲁氏菌初步鉴定,再用传统生物学分型方法进行确证,结合饲养家畜血清学和病原学检测结果分析患者的流行病学特征。结果 Vitek 2 compact鉴定12株为羊种布鲁氏菌,4株为人苍白杆菌。传统生物学分型方法鉴定11株为羊种布鲁氏菌3型,5株为猪种布鲁氏菌3型。菌株对应的16例病例中2012年1例,2013年2例,2014年4例,2015年1例,2016年2例,2017年6例,分布在东方市、临高县、海口市、万宁市、乐东县、定安县等地。同时对疫区东方市745份羊血清进行布鲁氏菌血清抗体检测,阳性47例(6.3%),从东方市病羊采集的标本中分离到羊种布鲁氏菌3型。结论 Vitek 2 compact是一种简单、方便的布鲁氏菌鉴定方法,但不能替代传统生物学分型方法;海南地区布病主要流行的菌种为羊种3型及猪种3型,通过东方市2017年布病疫情,说明海南省有布病疫畜传染人的疫情,布病防控形势严峻。
英文摘要:
      Objective To understand the epidemiological characteristics of brucellosis in Hainan province. Methods Automatic microbial identification system of Vitek 2 compact was used for the preliminary identification of 16 brucellosis cases in Hainan province from 2012 to 2017, and further confirmation was performed with traditional biological typing methods. The epidemiological and clinical characteristics of the patients were analyzed in combination with the results of serological and etiological tests for raised livestock. Results Vitek 2 compact detection results showed that 12 strains were Brucella (B.) melitensis and 4 strains were Ochrobactrum anthropi. Traditional biological typing methods showed that 11 strains were B. melitensis biovar 3 and 5 strains were B. suis biovar 3. Sixteen cases were found in Dongfang, Lingao, Haikou, Wanning, Ledong and Ding'an with 1 case in 2012, 2 cases in 2013, 4 cases in 2014, 1 case in 2015, 2 cases in 2016 and 6 cases in 2017 respectively. At the same time, 745 sheep serum samples from the epidemic area (Dongfang) were collected for Brucella serum antibody detection, in which 47 were positive (6.3%). And B. melitensis biovar 3 was isolated from samples collected from sick sheep in Dongfang. Conclusions Vitek 2 compact is an simple and convenient method for Brucella identification, but it cannot replace traditional biological typing methods yet. The major epidemic strains of Brucella in Hainan were B. melitensis biovar 3 and B. suis biovar 3. The epidemic of brucellosis in Dongfang in 2017 indicated that brucellosis had spread from animal to human in Hainan, and it is very important to strengthen the prevention and control of brucellosis in Hainan.
查看全文   Html全文     查看/发表评论  下载PDF阅读器
关闭