| 浙江省青田县病毒性肝炎调查组.青田县人群乙型肝炎表面抗原携带情况的调查[J].Chinese journal of Epidemiology,1983,4(2):79-82 |
| 青田县人群乙型肝炎表面抗原携带情况的调查 |
| Investigation on Human Carriage of HBsAg in Qingtian County |
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| Abstract: |
| 1980年7~10月对浙南山区青田县5,168人进行了乙型肝炎表面抗原、抗体系统和e抗原、抗体系统的调查,人群HBsAg阳性率为12.5%,农村不比城镇低;男性明显高于女性,低年龄组高于高年龄组;职业上无显著差异,抗-HBs阳性率性别间无显著差异,而阳性母亲生的女孩明显多于H BsAg阳性母亲所生女孩,支持London的假设。HBsAg阳性者呈显著的家庭聚集现象。母亲HBsAg阳性的家庭,其子女阳性率高于父母亲HBsAg阴性家庭的4倍以上;高于父亲HBsAg阳性,母亲HBsAg阴性家庭的3倍多。HBsAg阳性SGPT升高为10.52%,高于HBsAg阴性者(1.48%)。e抗原、抗体系统不具有流行病学意义。调查结果与国内外报道基本相一致。 |
| English Abstract: |
| From July to Oct. 1980,5,168 people living in Qingtian County, located in the mountainous area of southern Zhejiang Province were examined for HBsAg—Ab system and HBsAg—Ab system. The results indicated a positivrity rate of 12.5% for HB-sAg, The percentage of antigen in rural district was not lower than that of urban. Percentage of patients HBsAg in male was significantly higher than that in female and that of youngers was found higher than that of the higher age—group.No significant difference was found among people with different profession. As regard to anti-HBs antibody, no significant difference was revealed between male and female. The anti-HBsAg-positive mothers gave birth to more daughters than those not carrying HBsAg.This observation supported the London hypothesis. The HBsAg carrier state had a tendency to aggregate in certain family. Children from a HBsAg-positive mother would have a rate of positivity 4 times higher than those with HBsAg negative parents, and more than three times as high as those from positive father only.The SGPT value in HBsAg carriers was found to be elevated to a certain extent (10.52%) than HBsAg-negative people(1.48%). In regard to “e” Ag-Ab system, the author found no epidemiological significance. Tlie data presented here appears in agreement with that reported elsewhere. |
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