| 陈伯权,刘琴芝,周国芳.我国一些地区人血清的虫媒病毒抗体调查[J].Chinese journal of Epidemiology,1983,4(5):263-266 |
| 我国一些地区人血清的虫媒病毒抗体调查 |
| Arbovirus Antibody Survey of Human Sera in China |
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| Abstract: |
| 本文调查了28个省、市、自治区的人血清对18种虫媒病毒抗原的血凝抑制抗体,发现我国广大地区主要存在乙组虫媒病毒,但也存在甲组和布尼安病毒的可能。甲组病毒的抗体阳性数占总阳性数的16.7%(58/347),新疆、青海、黑龙江、山西、福建、甘肃省占甲组虫媒病毒抗体阳性数的84%。布尼安病毒中特别是Aino病毒的抗体阳性率较高,占总阳性数的12.7%(45/347),黑龙江8/10人阳性,其HI滴度都大于1/80,最高为1/1280,平均滴度为1/320,黑龙江、新疆、福建、北京占布尼安总阳性数的70%。乙组虫媒病毒则以乙脑为主。但其它病毒的抗体如Zika、 Kunjin的抗体阳性也很高,故推测我国除已知有乙脑、森脑、登革热外,尚有其它乙组虫媒病毒存在的可能。 |
| English Abstract: |
| 347 samples of human sera collected from different parts of China (except Tibct and Taiwan) were tested with hemagglutinationinhibition test against 18 antigens of Arboviruses including group A (Alphavrus): VEE,WEE, SF,GETAH, CHIK, SINDBIS; Group B (Flavivirus): JE, WN,DEN-2, SEPIK, ZIKA, KUNJIN, KFD, TEMBUSU, POWASSAN, Langet; Bunyamwera supergroup (Simbu group): AINO, INGWAVUMA. Sera were found to have antibodies not only against group B but also against group A and Bunyamwera supergroup arboviruses, The result indicated that group B arboviruses were prevalent in China, especially JE. But Kunjin and Zika viruses were first discovered to have a high prevalence rate especially ia Xinjiang and Qinghai areas. Group A arbovirus was not as prevalent as group B but there is still a sera positive rate of 58/347 (16.7%).Bunyamwera supergroup arbovirus antibody was first discovered in China. It is very interesting to find that there is a high prevalence rate against Aino virus, especiially in Heilongjiang Province, 8/10 human sera were positive, the HI titer was 1/80-1/1280 with an average titer of 1/320. The results showed that there are probably group A, Bunyamwera supergroup and other group B arboviruses in addition to JE DEN RSSE in China. |
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