| 李世清,罗兆庄,王以艮,倪大石,沈宏开,余荣汉.流行性出血热患者病后血清中特异性抗体持续时间的调查[J].Chinese journal of Epidemiology,1983,4(5):285-287 |
| 流行性出血热患者病后血清中特异性抗体持续时间的调查 |
| An Observation on the Persistent Period of Specific Antibodies in EHF Patients' Convalescent Sera |
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| Abstract: |
| 本文利用我国分离的EHF病毒适应A-549细胞制作的抗原片,应用IFAT法对EHF患者病后血清中特异性抗体持续时间作了调查。共调查了123份血清,阳性64份,阳性率52.03%,其中70%以上病人病后4年之内血清中含有特异性抗体,5年以后明显下降,20~22年尚有31.82%,可检出特异性抗体;病后4年之内阳性血清中有40%滴度在1:40以上,高者大于1:640, 5年之后滴度明显下降,此后维持在较低的水平。 |
| English Abstract: |
| A549 cell culture of EHF causative agent (isolated from China) as EHF antigen was used to detect antibodies of EHF patients' convalescent sera by indirect FA test. The total positive rate of IF antibodies of sera obtained from different periods of EHF patients was 52.03% (64/123). More than 70% of sera of EHF patients who had been attacked before 4 years were found IF antibodies. The titers of 40% of the above sera were 1:40-1:640 and the titers rapidly decreased in the fifth year after infection. However, IF antibodies were detected in 31.82% of EHF patients who had been attacked 20-22 years ago. |
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