| 吴霆,徐福根,陈用琴,李次白,任伟奇,郭承荫,徐特璋.诸暨麻疹联防区麻疹流行特征研究[J].Chinese journal of Epidemiology,1984,5(2):68-71 |
| 诸暨麻疹联防区麻疹流行特征研究 |
| An Observation on Epidemiological Characteristics of Measles in Zhuji Joint Prevention Area |
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| Abstract: |
| 自1973年9月至1981年8月，以沪191液体麻苗为主在诸暨县等十个县市（约750万人）开展麻疹联防工作，结果：1.发病率比未接种麻苗前13年（1954~1967）和开展麻苗接种但未开展联防以前6年（1967~1973）分别下降93.8%和77.9%；2.季节高峰后移约一个月；3.发病向大年龄组（≥15岁）转移；4.血清抗体阳性率高于90%，HI抗体GMT值一直维持在1：10~1：20之间，而麻疹发病率为6/10万的诸暨县则为1：5~1：11。作者认为在目前尚不能消灭麻疹的情况下，如能将麻疹的年平均发病率控制在50~100/10万之间，则人群免疫状态比较理想。 |
| English Abstract: |
| From september 1973 to August 1981, a measles control campaign was carried among a population of 7.5 million people in Zhuji county and its nine nerghbouring counties and cities.Several live measles vaccines (Chiefly S191) of liquid form was being used for mass immunization.The result showed:1) The morbidity of measles decreased by 93.8%as compared with 1954-1967 when measles vaccines had not been available,and by 77.9% as compared with 1967~1973 when the mass-scale prophylaxis had not been carried out,2) The epidemic scason peak delayed for about one month,3) The measles patients age distribution shifted to older age group (≥ 15 years-old,4). The serum positive rate was higher than 90% and the GMT of HI antibody lay in average between 1:10 and 1:20,while in Zhuji county,with a diseased incidence of 6/100,000 the GMT of HI antibody between 1:5 and 1:11.In the author's opinion,if it is not possible to eliminate the measles completely under the present conditions it would be desirable to decrease the incidence down to 50~100/100,000. |
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