邹翘华,陈贵春,郑越萍,祝朝芬.甲型肝炎病毒感染的血清流行病学研究[J].Chinese journal of Epidemiology,1984,5(6):329-331 |
甲型肝炎病毒感染的血清流行病学研究 |
A Seroepidemiological Study of Hepatitis A Viral Infection |
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Abstract: |
对543例城、乡正常人群甲肝IgG抗体的IAHA检测指出阳性率为64.8%。男女差异无显著性(P>0.05)。约半数感染人群发生在10岁以前,到成年时已超过80%。农村较城市更高(P<0.001),多数感染(73.2%)发生在10岁以下的小年龄人群,城市感染则多发生在较大年龄人群,与农村不同。表明甲肝感染普遍而严重。包括幼儿在内的青少年应是防止甲肝感染的主要对象,控制这些易感人群集中单位的爆发流行,是降低甲肝发病的有力措施。成人的群体免疫力较强,主要是及时发现,处理好散在发生的甲肝患者及其密切接触的易感人群,防止造成流行是有积极意义的。 |
English Abstract: |
Sera of 543 healthy persons from urban and rural areas in Guiyang, Guizhou province were tested for antibody against hepatitis A antigen (anti-HAV IgG) by means of immune adherence hemagglutination. Among them 64.8% were anti-HAV positive. There was no significant difference in antibody level between males and females (p>0.05). Although the anti-HAV positive rates in the rural population were much higher than that in the urban population (p<0.001), the infection rates increased as age went up. Half of the persons under-10 years were infected. Among adults, the anti-HAV positive rates were more than 80%. However, there were differences in the two areas. Hepatitis A mainly infcted older children in urban areas while it mainly involved the younger ones (including the youngest) in rural areas. |
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