| 武光林,耿贯一,张安玉,杨慧敏.各种生育因素对不同年龄妇女发生乳腺癌的危险性[J].Chinese journal of Epidemiology,1986,7(2):65-69 |
| 各种生育因素对不同年龄妇女发生乳腺癌的危险性 |
| The Risk of Developing Mammary Carcinoma at Different Age in women in Relation to Various Fertility Factors |
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| Abstract: |
| 在天津市区家访的506例女性乳腺癌患者和由医院配对的病例对照研究中,研究了与诊断年龄有关的月经、生殖因素。在分析中按诊断年龄把病例和相应的对照分成<45,45~54, ≥ 55岁三个组。初产年龄晚在各年龄组均增加乳腺癌的危险性。在<55岁年龄组另一个危险因素为初潮年龄早,而在 ≥ 45岁年龄组则与低产次、无生育有关。经按层次对潜在的混淆因素调整后,乳腺癌与哺乳、结婚年龄、末产年龄和初末产间隔无关。 |
| English Abstract: |
| The factors associated with age at diagnosis in menstruous and reproductive histories were studied in 506 female patients with breast cancer and matched controls from hospitals in Tianjin. In the analysis the patients and controls were divided into three age groups:under 45 years old, 45-54, and 55 and olde. Late age at first birth was linked to the increased risk of breast cancer in all three age groups. Among women under age 55 another risk factor was early age at menarche. But among women aged 45 and older, the facters associated with increased risk were nulliparity and less parity. After adjusted for potential confounding variables by stratification, the breast cancer risk was unrelated to lactation, age at first marriage, age at last birth, and interval from age at first birth to age at last birth. |
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