| 汪慧民,谢明,骆林,王莉,王士奇.武汉地区不同年龄组巨细胞病毒抗体的研究[J].Chinese journal of Epidemiology,1986,7(2):74-77 |
| 武汉地区不同年龄组巨细胞病毒抗体的研究 |
| A Study of Antibodies Against Cytomegalovirus in Different Age Groups in Wuhan District |
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| Abstract: |
为便于与WHO组织调查CMV抗体情况比较,采用AD169株作补结抗原,检测武汉地区各年龄组正常人血清中补结抗体595例,结果2~3月婴儿阳性率低(29.41%),与国外资料相近,但4~6月小儿阳性率(78.57%)显著高于国外大多数国家的。25岁以上年龄组阳性率显著高于以下的,P<0.001。男女性别间,5岁以前各年龄组差异不显,P>0.3。5岁以上各年龄组,女性均高于男性,P<0.001。女性15岁以上组阳性率显著高于以下者,P<0.001。脐血阳性率和女性15~39岁各年龄组,差异不显著,P>0.3。
本资料说明我国CMV感染较普遍,各年龄组均有,这对进一步探索CMV致胎儿畸形提供了依据。 |
| English Abstract: |
Healthy people of various ages from 2 months to 79 years old in Wuhan were investigated for CMVCFAb by testing samples of serum and cord blood and the results were compared with those reported by World Health Organization in other countries. The results showed that the positive rate of 2-3-month infants was as low as that of other countries. 4-6 month infants have higher positive rate than the same age group of most foreign countries. People less than 25 years old had significantly lower positive ratethan that above 25 years. (P<0.001). No significant difference was found in children of both sexes under 5 years age and those above 5 years of age consistently had higher rate of CMV-CFAb in females. All of these differences are statiscally significant (P<0.001). There was a higher prevalence of CMV-CEAb in females above 15 years of age than under 15 years (p<0.001). Positive rate of cord blood were in agreement with those females of 15 to 39 years age group (P>0.3). Geometric mean titers of CMV-CFAb was 14.3.
The result indicates that CMV infection is much more common. It is evident that CMV may-be one of the further causative agents responsible for abnormality of fetus. |
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