| 魏善波,周祖岳,胡凯加,易祥,何华先.华容县农村肝癌病例对照研究[J].Chinese journal of Epidemiology,1987,8(2):84-87 |
| 华容县农村肝癌病例对照研究 |
| A Case-Control Study of Liver Cancer in the Rural Area of Huarong County, Hunan Province |
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| Abstract: |
| 为探讨肝癌病因,我们于1985年6月在华容县农村完成了99对随机样本的肝癌病例对照调查。病例对照同居一个大队,在性别、死亡年龄和死亡时间上配比。调查的因素有疟疾史、血吸虫史、肝炎史、家族史、饮酒史、接触农药史、饮食史和水源类型,运用OR、χ2和χ2MH进行统计处理.结果配比调查发现疟疾(OR=2.08,χ2=4.90)、遗传(OR=18.0,χ2=16.06)、饮酒(OR=1.88,χ2=4.59)与肝癌有关,其它因素无关联;进一步分析还证实,疟疾发作次数与肝癌之间,饮酒度与肝癌之间存在剂量反应关系。 |
| English Abstract: |
| A case-control study involving a sample of 99 pairs which were randomly and respectively selected from farmers who died of liver cancer or from other dead individuals not suffering from liver cancer, hepatosis or accidants during 1980~1984 was carried out in order to investigate the etiology of liver cancer in Huarong County, Hunan Province in June, 1985. The dead controls were matched to the dead cases on sex, age at death and year of death. Most of both controls and cases lived in the same area but not in the same village and their next-of-kin were interviewed by trained interviewers. A detailed questionuaire on exposure variables such as histories of malaria, heredity, hepatitis, schistosome, consumer of liquor, insecticide, some aspects of diet and the type of drinking water was used. Using odds ratio, χ2 test and χ2 MH test, the writers reported in their study that the results, with regard to varibles of malaria (OR=2.08, χ2=4.90, P<0.05) heredity (OR=18.0, χ2=16.06, P<0.01) and consumer of liquor (OR=1.88, χ2=4.59), P<0.05), were statistically significant and there were no significant differences between the two groups in the other variables. The results also showed dose-response relationship between the number of malaria attacks or amount of liquor consumed and liver concer. |
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