Abstract
彭道仪,苏卓娃,刘利铭,胡彩清,刘小桂,戴裕海.间接荧光抗体试验在血吸虫病流行病学调查中的应用[J].Chinese journal of Epidemiology,1988,9(1):46-48
间接荧光抗体试验在血吸虫病流行病学调查中的应用
The Application of Indirect Fluorescent Antibody Test (IFAT) in Epidemiological Survey on Schistosomiasis Japonica
  
DOI:
KeyWord: 日本血吸虫病  流行病学  间接荧光抗体试验(IFAT)  血清流行病学
English Key Word: Schistosomiasis japonica  Epidemiology  IFAT (Indirect Fluorescent Antibody Test)  Sero-epidemiology
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Author NameAffiliation
Peng Daoyi Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
苏卓娃 Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
刘利铭 Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
胡彩清 Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
刘小桂 Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
戴裕海 Institute of Parasitic Disease, Hubei Academy of Medical Science, Wuhan 
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Abstract:
      在一个血吸虫病重疫区村内,作者每年对6~15岁年龄儿童进行间接荧光抗体试验(IFAT),五年纵向观察结果显示:IFA反应率与GMRT的变化均与粪检阳性率呈正相关。IFA反应率曲线理论估计值ŷ=10.090e0.036x(γ=0.972),GMRT的ŷ值=0.765e0.044x(γ=0.994)。本文认为该法较其它方法敏感,可用来推测当地粪检阳性率或新感染率的变化,具有考核防治效果与预测疫情的参考价值。
English Abstract:
      IFAT was carried out in school-age children from 6 to 15 years old to study the trends of epidemic situation.In a serious endemic village with schistosomiasis japonica. This work was performed year after year for five years. The results of longitudinal observation showed that both the IFAT positive rate and GMRT value presented positive correlation with the positive rate of stool examination. ŷ (of IFA positive rate)=10.909e0.036x (γ=0.972), ŷ (of GMRT)=0.765e0.044x (γ=0.994). The authors suggested that the method may estimate the positive rate of stool examination or incidence of the locality and as the reference value to examine the effect of control and to estimate the epidemic stituation.
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