| 米竹君,朱万孚,韩纯学,张国庆,钟海林,何培英,田庚善.115例HBsAg携带者的聚合人血清白蛋白PHSA受体的研究[J].Chinese journal of Epidemiology,1988,9(2):80-83 |
| 115例HBsAg携带者的聚合人血清白蛋白PHSA受体的研究 |
| Study on Polymerized Human Serum Albumin Receptor (PHSA-R) in 115 HBsAg Carriers |
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| DOI： |
| KeyWord: HBsAg携带者 聚合人血清白蛋白（PHSA）受体 酶联免疫吸附试验 |
| English Key Word: HBsAg carrier Polymerized human serum albumin receptor (PHSA-R) ELISA |
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| Abstract: |
| 用ELISA方法检测HBsAg携带者的PHSA受体,共检测406份血清。HBeAg阳性者中PHSA受体的阳性率为62.2%(28/45),正常人中阳性率为1.25%(1/80)。HBsAg携带者的PHSA受体测定与HBV-DNA试验结果一致率为88.09%。115例的HBsAg携带者的PHSA受体的年龄分布是0~20岁组PHSA受体阳性率为63.04%(29/46),21~40岁组20.0%(9/45),41岁以上8.33%(2/24)。(χ2=51.31,P﹤0.005)。以小年龄组阳性率最高。9户HBsAg携带者家庭中46名HBsAg阴性成员中无一例PHSA受体阳性。 |
| English Abstract: |
| The PHSA-R was detected by ELISA method in 115 HBsAg carriers. The positive rate PHSAR was 63% (28/45) in HBeAg positive sera. But only 1 out of 80 HBsAg negative health subjects was PHSA-R positive. We also Compared the results of this ELISA method with HBV-DNA assay. The coincident rate was 88.09%. The positive rate of PHSA-R in different age groups was: 0-20-69.0% (29/46), 21-40-20.0% (9/45), over 41-8.33% (2/24). (χ2=51.31 P﹤0.005), A significant difference was found among these three age groups. It was intrest that there was no PHSA-R positive serum in 46 HBsAg-negative sera from 9 HBsAg carriers' families. |
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