| 买凯,金志宏,熊诗松,马丽丽,陈洪涛,赵国龙,田庚善,舒昌杰,段恕诚,崔振宇,叶梅君,熊汇慈,凌竟熙,白峰,丁正荣,李岱,董祥稼,姚桢,周才仁,邱德贵.我国部分地区δ型肝炎调查研究[J].Chinese journal of Epidemiology,1989,10(1):21-23 |
| 我国部分地区δ型肝炎调查研究 |
| Study on Hepatitis Delta Virus Infection in China |
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| DOI： |
| KeyWord: δ型肝炎病毒 抗-δ抗体 乙型肝炎表面抗原亚型 |
| English Key Word: Hepatitis delta virus Anti-Delta Subtypes of HBsAg |
| FundProject: |
| Author Name | Affiliation | | Mai Kai | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 金志宏 | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 熊诗松 | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 马丽丽 | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 陈洪涛 | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 赵国龙 | Henan Institute of Medical Sciences, Henan Medical University, Zhengzhou | | 田庚善 | 北京医科大学第一附属医院 | | 舒昌杰 | 西安医科大学附属医院 | | 段恕诚 | 上海第一医科大学儿童医院 | | 崔振宇 | 北京第一传染病院 | | 叶梅君 | 华西医科大学 | | 熊汇慈 | 华西医科大学 | | 凌竟熙 | 新疆医学院第一附属医院 | | 白峰 | 内蒙古自治区卫生防疫站 | | 丁正荣 | 广西壮族自治区卫生防疫站 | | 李岱 | 新疆哈密红星医院 | | 董祥稼 | 中国医科大学第一附属医院 | | 姚桢 | 哈尔滨医科大学附属医院 | | 周才仁 | 中国人民解放军一八〇医院 | | 邱德贵 | 华西医科大学 |
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| Abstract: |
| 本文应用酶联吸附(EIA)及固相放射免疫(RIA)法对我国11个省、市、自治区共1 027例,HBsAg阳性者检测了抗-δ抗体。发现北京、上海、广西、四川、黑龙江、福建、辽宁及河南八省,市634例中未检出阳性;内蒙、新疆及西藏自治区393例中17例阳性(4.3%)。这些地区慢性活动性肝炎和慢性迁延性肝炎中抗-δ阳性率明显高于慢性无症状HBsAg携带者。提示我国HDV感染呈现明显的地方性散发特征及HDV感染对慢性肝炎的形成具有重要意义。 |
| English Abstract: |
| Antibody to the delta antigen (anti-delta) was defected by using ELISA and RIA in 1027 HBsAg-positive persons distributed over 11 pro-vinces, municipalities, and autonomous regions in China. No positive of anti-delta was found in 634 cases in Beijing, Shanghai,Guangxi, Sichuan,Heilongjiang, Fujian, Liaonin, and Henan, of 393 cases in Inner Mongolia, Xinjiang and Tibet, 17(4.3%) were positive. In these regions, the positive rate of anti-delta in CAH and CPH was much higher than that in chronic HBsAg carriers.It was suggested that HDV infection was characterized by endemic and sporadic features in China and it was important in the pathogenesis of chromic hepatitis B. |
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