王学良,徐慧文.原发性肝癌病因多因素分析:HBV感染与其它因素相结合在肝癌发生中的作用[J].Chinese journal of Epidemiology,1989,10(2):82-85 |
原发性肝癌病因多因素分析:HBV感染与其它因素相结合在肝癌发生中的作用 |
Multiple Pathogenic Factors Analysis on Primary Liver Cancer the Role of HBV infection Combined with other Risk Factors in the Occurrence of PLC |
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DOI: |
KeyWord: 原发性肝癌 HBV感染 病因因素 协同效应 |
English Key Word: PLC HBV infection Etiologic factor Synergic effect |
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Abstract: |
本文对102例原发性肝癌(简称肝癌)病人和两组对照进行了病例-对照和血清流行病学研究。结果进一步证实肝癌发病与HBV感染密切相关;精神创伤和饮酒可能也是与肝癌发病有关的危险因素。在协同效应分析中,HBV感染及免疫两类指标与其它因素组合时呈现完全不同的结果,提示可能还有许多其它因素参与并通过交互作用显著加强某些致肝癌因子的效应。 |
English Abstract: |
To assess the roles of some suspected etiological factors in the pathogenic course of primary liver cancer (PLC), a casecontrol and seroepidemiologic study was conducted in 102 cases of PLC patients and two control groups. The result provides further data to support the hypothesis that PLC is closely associated with HBV infection. The study also shows that psychic trauma and habitual drinking may be regarded as the risk factors for PLC. Moreover, it is noticeable that a significant synergic effect is observed when some factors work together, This probably indicates that many other factors also play an important part in the pathogenic course of PLC. |
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