| 刘振强,张延学,谢慰杖,赵世立,黄宝童,李爱萍,陈玮,李文,王奉伟,王淑凤.国产乙型肝炎血源疫苗免疫效果及持久性观察[J].Chinese journal of Epidemiology,1989,10(4):203-205 |
| 国产乙型肝炎血源疫苗免疫效果及持久性观察 |
| A Survey of the Immune Effects and Persistence of Chinese Produced HB Bloodorigin Vaccines |
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| DOI： |
| KeyWord: 乙型肝炎疫苗 乙型肝炎表面抗体 安全性 免疫效果 免疫持久性 |
| English Key Word: HB vaccine Anti-HBs Safety Immune effect Immune persistence |
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| Author Name | Affiliation | | Liu Zhenqiang | Shandong Provincial Epidemic Prevention Station, Jinan | | 张延学 | Shandong Provincial Epidemic Prevention Station, Jinan | | 谢慰杖 | Shandong Provincial Epidemic Prevention Station, Jinan | | 赵世立 | Shandong Provincial Epidemic Prevention Station, Jinan | | 黄宝童 | Shandong Provincial Epidemic Prevention Station, Jinan | | 李爱萍 | Shandong Provincial Epidemic Prevention Station, Jinan | | 陈玮 | Shandong Provincial Epidemic Prevention Station, Jinan | | 李文 | Shandong Provincial Epidemic Prevention Station, Jinan | | 王奉伟 | Shandong Provincial Epidemic Prevention Station, Jinan | | 王淑凤 | Shandong Provincial Epidemic Prevention Station, Jinan |
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| Abstract: |
| 本文对卫生部北京生物制品研究所生产的843-1批乙肝疫苗的免疫效果及持久性进行了为期三年的人群系统观察,结果表明疫苗接种人体安全,反应轻微,抗原性及近期免疫效果较好,免疫后三年抗-HBs阳性率及抗-HBsP/N值则有较大幅度的下降,提示在免疫后第三年应进行加强注射,以提高机体的免疫水平。 |
| English Abstract: |
| A three-year systematic community surrey was curried out in order to observe the immune effects and persistence of the 843-1 batch of HB vaccines produced by Beijing Biological Products Research Institute affiliated with the Ministry of Public Health.The results showed that the vaccination was safe and the reactions were slight.The antigenicity and short-term immune effects were good.After three years the positive rate and the P/N value of antiHBs dropped considerably.This suggests that after 3 years of immunization, booster injection should be given to improve the immune level. |
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