Abstract
陈重昇,俞莉,张汝黻,杨平.福建省莆田市黄石乡饮用水亚硝胺污染的调查[J].Chinese journal of Epidemiology,1989,10(6):359-362
福建省莆田市黄石乡饮用水亚硝胺污染的调查
Investigation on Nitrosamine in Drinking Water in Huang Shi——A High-risk Area of Stomach Cancer in Fujian Province
  
DOI:
KeyWord: 饮用水  亚硝胺
English Key Word: Drinking water  Nitrosamine
FundProject:
Author NameAffiliation
Chen Chongsheng Beijing Institute for Cancer Research 
俞莉 Beijing Institute for Cancer Research 
张汝黻 Beijing Institute for Cancer Research 
杨平 福建省莆田市医学科学研究所 
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Abstract:
      福建省莆田市黄石乡是我国胃癌高发区之一。流行病学调查表明这与提供居民饮用水的木兰溪水系受严重污染有关。本文对32份沿此水系不同地点采集的冬、夏两季水样亚硝酸根及亚硝胺进行了测定。经GC-TEA和LC-TEA共检出6种致癌亚硝胺及3个非挥发性亚硝胺未知峰。冬季因受上游工厂污水的污染,水样中亚硝胺的种类及含量皆明显高于夏季,多层沙石过滤不能有效降低其含量。饮用水的亚硝胺污染可能与该地上消化道癌的高发有关。
English Abstract:
      Huang Shi town in Fujian province is one of the high-risk area of stomach cancer in China with a standard mortality rate of 61.19/100 000 in males.Epidemiologic survey showed that it was related to the severe contamination of Mu-Lan river system by which the drinking water for the residents was provided.
Thirth-three water samples in the summer and winter times, filtrated and unfiltrated, from different spots along this river system were collected. The concentrations of nitrite and nitrosamine were determined. NDMA, NDEA, NDPA, NDBA, NPIP and NMOR by GC-TEA and three unknow peaks preliminarily identified as non-volatile nitrosamine by LC-TEA could be detected in these samples. The kinds and the content of nitrosamine in the samples collected in the winter time were all significantly higher than those collected in the summer, P values were all less than 0.01. Its possible significance in the causes of gastrointestinal tumors is discussed.
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