| 周详,徐道寅,俞学铭,胡卫星.冠心病人患胆结石危险因素配对调查[J].Chinese journal of Epidemiology,1990,11(1):5-8 |
| 冠心病人患胆结石危险因素配对调查 |
| Matched Investigation of Risk Factors about the Coronary Heart Patients with Gallstones |
| Received:January 09, 1989 Revised:March 10, 1989 |
| DOI： |
| KeyWord: 冠心病 胆结石 病例对照研究 |
| English Key Word: Coronary heart disease Gallstone Case-control study |
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| Abstract: |
调查75例胆结石病例和75例对照。两组对象均为冠心病患者。结果表明:冠心病人患有胆结石症的病例组,既往有胆囊炎、慢性肠道疾患及家族胆结石史的阳性率明显高于冠心病人不患有胆结石症的对照组(P<0.05及0.01),比值比(OR)分别为4.22、9.00和6.00。调查结果同时表明:两组对象高血清脂质水平、过度肥胖、摄入高胆固醇及脂肪的阳性率无显著差异(P>0.05),且均未服用过安妥明类药物。
本文提示:冠心病人患胆结石与一般人群可能有相同的好发因素:单纯脂质代谢失调与胆结石的发生无直接联系;脂质代谢失调与服用某类药物的协同作用可能是冠心病人患胆结石又一好发因素。 |
| English Abstract: |
Serenty-five cases of coronary heart disease with gallstones and another 75 cases without gallstones as controls were studied.The positive rates of previous cholecytitis and chronic intestinal diseases, and familial history of gallstone in the first group were obviously higher than those in the control group (P<0.05 & 0:11). The odd ratio (OR) was 4.22, 9.00 and 6.00, respectively.
The re was no difference in high serous lipid level, overobesity, high cholesterol and fat intake (P>0.05) neither group took clofi-rrate. It demonstrated that susceptible factors for coronary heart disease patients to develop gallstones are probably the same as in general population. The imbalence of lipoid metabolism had no direct associate with gallstoes. The synergistic action of the imbatance of lipid metabolism and administration of some kinds of medicine might be a susceptible factor for corunary heart disease patients to develop gallstones. |
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