| 高恩明,叶人邦,丁绍卿.SPA协同凝集试验快速诊断流脑的研究[J].Chinese journal of Epidemiology,1990,11(3):167-169 |
| SPA协同凝集试验快速诊断流脑的研究 |
| Rapid Diagnosis of Epidemic Cerebrospinal Meningitis by Co-agglutination |
| Received:August 05, 1987 |
| DOI： |
| KeyWord: 协同凝集试验 流行性脑脊髄膜炎 |
| English Key Word: Co-agglutination Epidemoic cerbrospinal meningitis |
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| Abstract: |
| 本文采用协同凝集(COA)试验的方法检査流行性脑脊髓膜炎病人脑脊髓液(CSF)、血清、尿液中的A群脑膜炎奈瑟氏菌多糖抗原。共检测CSF I95份,血清214份,尿69份。其中从CSF或血液分离培养出A群脑膜炎奈瑟氏菌病人的标本阳性率分别是:CSF 81.2%;血清64.6%;尿50.0%。而分离培养出B群脑膜炎奈瑟氏菌、肺炎链球菌等病人的CSF、血清、尿标本则全部阴性。证明了COA试验具有良好的敏感性与特异性。COA有快速、简便的优点,而且不需要特殊的仪器设备。 |
| English Abstract: |
| Group A meningococcus polysrccharide antigen from cerebrospinal fluid (CSF),serum and urine were detected by Co-agglutination (COA) method.In total 478 samples, CSF, sear and urines 195, 214, and 69 samples wrer detected respectively.COA positive rate of CSF were 81.2%, serum were 64.6% and urine were 50%, in the patients from whom group A bacteria were isolated. but the samples from which group B meningococcus, penumococcus or other isolates positive showed negative in COA. A good sensitivity and specificity of COA method have been proved in this paper. The advantages of COA method were rapid, simple and could be easily performed in ordinary laboratory conditions. |
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