| 谭红专,肖亦璟,吴彭年,汤森林,汤学民.某农场HBV感染的血清流行病学研究[J].Chinese journal of Epidemiology,1990,11(6):334-337 |
| 某农场HBV感染的血清流行病学研究 |
| A Sero-epidemiological Study on HBV Infection in a Farm |
| Received:January 21, 1989 |
| DOI： |
| KeyWord: HBV HBsAg e抗原 HBV DNA |
| English Key Word: HBV HBsAg HBeAg HBV DNA |
| FundProject: |
| Author Name | Affiliation | | Tan Hongzhuan | Department of Epidemiology, Hvnan Medical University, Changsha | | 肖亦璟 | Department of Epidemiology, Hvnan Medical University, Changsha | | 吴彭年 | Department of Epidemiology, Hvnan Medical University, Changsha | | 汤森林 | Department of Epidemiology, Hvnan Medical University, Changsha | | 汤学民 | Department of Epidemiology, Hvnan Medical University, Changsha |
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| Abstract: |
| 对777份血清标本分别用敏感的SPRIA、ELTSA和斑点杂交法检测HBsAg、抗-HBs、抗-HBc、HBeAg、抗-HBe和HBV DNA。检测结果表明:HBeAg阴性者中仍有9.33% HBV DNA阳性,因此仅检测HBeAg并不能准确评价HBsAg携带者的传染性;在HBV总感染者中,男件HBsAg携带率明显高于女性,这种差异可能说明男女对HBV的反应性不同;在单项抗-HBs阳性者中,78.72%曾有过HBsAg和/或抗-HBc阳性史,因而提示这种单项抗_HBs阳性是HBV感染的特异表现。 |
| English Abstract: |
| A seroepidemiological study on HBV infection was carried out in a farm with a population of 777. HBsAg, anti-HBs and anti-HBc were tested with SPRIAi HBeAg and anti-HBe with ELISA and HBV DNA with spot hybridization. The results showed that:1.in HBeAg negative individuals, the positive rate of HBV DNA was 9.33%, as a result, the infectivity of HBsAg carriers could not be estimated accurately with HBeAg examination only; 2. among the total HBV infected individuals, the positive rate of HBsAg of the males was significantly higher than that of the females (51.38% vs 38.89%, P<0.005),indicating the difference of response to HBV between males and females; 3, in anti-HBs positive individuals, 42.53% were anti-HBs positive alone, of which, 78.72% had evidence of HBV infection four years before the examination, indicating that the majority of persons who had anti-HBs alone were specifically responsive to HBV. |
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