王平,郑全庆.子宫内膜癌病因学的病例-对照研究[J].Chinese journal of Epidemiology,1990,11(6):356-359 |
子宫内膜癌病因学的病例-对照研究 |
A Case-control Study on Endometrial Carcinoma |
Received:April 06, 1989 Revised:August 25, 1989 |
DOI: |
KeyWord: 病例-对照研究 子宫内膜癌 |
English Key Word: Case-control study Endometrial carcinoma Logistic regression |
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Abstract: |
用病例-对照的方法探讨了子宫内膜癌(以下简称内膜癌)发生的有关危险因素。调査内膜癌病例及对照共102对,详细了解了病例和对照的月经史、生育史、疾病史、避孕史等。发现怀孕次数少、生产次数少、月经初潮早、肥胖患内膜癌的相对危险性较大,均显示有剂量效应关系,经趋势性检验均有显著性意义。此外,髙血压、糖尿病、盆腔X线照射、刮宫、精神创伤亦可能与内膜癌发病有关。 |
English Abstract: |
In order to study the risk factors associated with endometrial carcinoma, a case-control study conducted in the First Affiliated Hospital of Xian Medical University, from July 1984 to June 1988. Interviews with 102 cases and 102 matched controls were made. The authors analyzed the data, by using odds ratio, χ2 test, χ2 test for trend and logistic regression-The results indicated that risk factors related to endometrial carcinoma might be early menarche. low frequecy of pregnancy, nulliparity or low parity and obesity. The factors of hypertension, diadetes, uterine curettage,fluoroscopy of pelvic cavity and mental trauma might also play a very iirportant role in the pathogenesis of endometrial carcinoma. There was no association between endometrial carcinoma and oral contraceptives, age of first birth, sterilization, leiomyoma of uterus. |
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