| 马志千,高殿庭,郄建忠.流脑A群多糖菌苗划片免疫九年流行病学效果观察[J].Chinese journal of Epidemiology,1991,12(2):69-71 |
| 流脑A群多糖菌苗划片免疫九年流行病学效果观察 |
| Observation on the Epidemiologic Efficacy for 9 Years on Epidemic Meningococcal Polysaccharide Vaccine of Group A by Districting Immunization Method |
| Received:May 29, 1989 Revised:June 23, 1990 |
| DOI： |
| KeyWord: A群流脑多糖菌苗 划片免疫 效果观察 |
| English Key Word: Polysaccharide Vaccine of epidemic Meningococcal Group A Districting immunization Observation of the efficacy |
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| Abstract: |
| 据预测1984年前后保定市为流脑大流行高峰年。为预防其出现,于1980~1984年对保定市区1~15岁儿童进行了两轮流脑多糖菌苗的按区划片免疫,接种率达80.01%。1985~1988年只对12~24月龄幼儿进行接种,接种率为97.15%。9年间免疫组观察833 333人发病4人,发病率为0.48/10万;对照组观察304 085人,发病25人,发病率为8.22/10万。菌苗保护率为94.16%,效果指数1:17.12。不仅有效地防止了保定市1984年大流行高峰年而且使1980~1988年连续9年流脑发病率维持在1/10万左右,是历史上最低水平。 |
| English Abstract: |
| According to previous studies, there might be a peak of epidemic meningitis in Baoding City in 1984. For preventing the epidemic, we carried out vaccination with meningococcal polysaccharide vaccine by districting immunization method during the 1980~1984 and then vaccination only to the children aged 12~24 months every year. The vaccination rate was 80.01% in 1980~1984 and was 97.15% in 1985~1988. During the 9 years, 833 377 children of vaccination group were observed, 4 of whom developed this disease, with an incidence of 0.48/100 000; and 304 085 children in the control group were observed, 25 of whom contracted this illness, with an incidence of 8.22/100 000. The protective rate of vaccine was 94.16% and the efficacy index was 1:17.12. This result showed that peak year of epidemic meningitis predicted in 1984 was prevented by vaccine immunization and the incidence of this disease was continuously kept less than 1/100 000 for 9 years. |
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