Abstract
李振广,王樾庭,姜俊启,韩丽君,谢长义,陆建帮,秦亚军,张作义.302例患过天花者HBV血清学调查研究[J].Chinese journal of Epidemiology,1991,12(2):83-86
302例患过天花者HBV血清学调查研究
Serologic Investigation of HBV in 302 Patients who had a History of Smallpox
Received:May 15, 1989  Revised:October 23, 1989
DOI:
KeyWord: 天花  乙型肝炎病毒  感染率
English Key Word: Smallpox  Hepatitis B Virus  Infection rate
FundProject:
Author NameAffiliation
Li Zhenguang The People's Hospital of Zhumadian County, Henan Province 
王樾庭 The People's Hospital of Zhumadian County, Henan Province 
姜俊启 The People's Hospital of Zhumadian County, Henan Province 
韩丽君 The People's Hospital of Zhumadian County, Henan Province 
谢长义 河南省肿瘤研究所免疫室 
陆建帮 河南省肿瘤研究所免疫室 
秦亚军 河南省驻马店地区卫生防疫站 
张作义 The People's Hospital of Zhumadian County, Henan Province 
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Abstract:
      对302例患过天花者这一特殊人群进行了HBV血清学调查,结果HBsAg阳性率(1.3%)分别显著低于对照组1(8.3%)和对照组2(8.6%)(P<0.001)。两对照组HBsAg阳性率无显著性差异(P>0.05)。患过天花者HBV感染率(19.2%)也分别显著低于对照组1(47.7%)和对照组2(51.3%)(P<0.001)。对上述三组细胞免疫功能测定结果,病例组玫瑰花结形成率及淋巴细胞转化率均分别显著高于两对照组。故认为上述结果是患过天花者细胞免疫功能增强,干扰乙型肝炎病毒感染所致。
English Abstract:
      This paper provides serologic investigation of HBV in 302 persons who had a history of smallpox in Zhumadian County.The results showed that the HBsAg positivity rate (1.3%)was significantly lower than those of the control group 1(8.3%) and 2(8.6%) (P<0.001). The HBsAg positivity rate between the two control groups had no significant difference (P>0.05). The HBV infection rate(19.2%) was also lower than those of control group 1 (47.7%) and 2(51.3%) (P<0.001).There was not much difference between the two control groups.The determination of cellular immunity showed that the rosette positivity rate (75.93%)and lymphocyte conversion rate (70.39%) of the patients' group were higher than those of control group 1(62.3%and 52.9%) and 2 (60.93% and 55.3%).It may suggested that patients having had smallpox might have enhanced cellular immunity which might interfere with HBV infection.
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