林静,张安玉,梁仲华.天津市原发性肝癌的危险因素[J].Chinese journal of Epidemiology,1991,12(6):346-349 |
天津市原发性肝癌的危险因素 |
A Study on Aetiological Factors of Primary Hepato-Carcinoma in Tianjin China |
Received:October 30, 1989 Revised:May 10, 1990 |
DOI: |
KeyWord: 原发性肝癌 HBV |
English Key Word: Primary hepato-carcinoma(PHC) HBV |
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Abstract: |
为探讨天津地区原发性肝癌可能的病因因素,本文调查了122例原发性肝癌病例及按1:1配对的医院对照,并对其中99对采集静脉血,检测HBV的血清学标志。结果表明:天津地区原发性肝癌的发生与HBV感染密切相关。HBV感染时机体的免疫状况是以后是否发展成原发性肝癌的一个重要因素。个人肝炎史、肝硬化史及家族肝癌史是原发性肝癌发生的危险因素。吸烟可能与肝癌有关,吸烟年限越长患肝癌的危险性越大。本研究未发现饮水类型、饮食习惯、饮酒、农药和毒物接触史、输血注射史与原发性肝癌有关。 |
English Abstract: |
In order to investigate the possible risk factors of primary hepato-carcinoma (PHC) in Tianjin, 122 clinical diagnosed PHC patients and matched hospital controls were interviewed and 99 pairs of their blood samples were examined for HBV. The findings confirmed the strong association between HBV infection and PHC.The individual's immune state during HBV infection might be an important factor for PHC development. Histories of hepatitis and cirrhosis and family history of PHC were risk factors of PHC.Cigarette smoking might have association with PHC.Smoking for more the years of the higher the risk of PHC. The present study did not find association between PHC and drinking water, dietary habits. alcohol consumption, histories of blood transfusion and injection, exposure to pesticides and poison. |
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